Kategorier: Alle - inhibitors - antibiotics

af Lauren Cagle 2 år siden

108

Spectrum of Activity

The text provides a detailed overview of various antibiotic classes and their respective spectrums of activity. It covers macrolides such as azithromycin and clarithromycin, noting their efficacy against atypicals and certain gram-positive and gram-negative bacteria.

Spectrum of Activity

Spectrum of Activity

Beta Lactams

Monobactams
Aztreonam
Carbapenems
Imipenem, Meropenem, Doripenem
Ertapenem

Anaerobes

No pseudomonas

No acinetobacter

Cephalosporins
Cephalosporin + Beta Lactamase Inh.

Ceftaz/Avi, Ceftol/Tazo

MDR Enterobacter

Ceftaroline (IV)

Gram Negative (HACEK)

Gram Positive (MSSA, MRSA, Strep, MRSE, NO Enterococcus)

4th Generation

Cefepime

Gram Positive (strep, MSSA)

3.5 Generation

Ceftazidime (IV), Cefiderocol (IV)

3rd Generation

Ceftriaxome, Cefdinir

Anaerobes (oral) *KAHOOT SAYS NONE*

HACEK DOC

Cefdinir NO Neisseria

Gram Positive (strep)

S. Pneumoniae DOC

2.5 Generation

Cephamycin, Cefoxitin, Cefotetan

Gram Positive (Strep A/B)

Cefuroxime

Cephalexin (PO), Cefazolin (IV)

Gram Negative (PEK)

Gram Positive (Staph, Strep, NO Entero)

MSSA DOC

Penicillins
Ureidopenicillins + Beta lactamase Inh.

Pip/Tazo

Anaerobes (oral and gut)

Gram negatives (inc. pseudomonas)

Gram positive (strep, Enterococcus)

Aminopenicllins + Betalactamase Inh.

Amp/Sulb, Amox/Clavul

Anaerobes (gut and oral)

Gram Negatives (No pseudomonas)

HIB DOC

Gram positive (strep, Enterococcus, Listeria)

Aminopenicillins

Ampicillin, Amoxicillin

Gram positive (Strep)

Enterococcus DOC (if susceptible)

Listeria DOC

Anti-staph PCN

Naf, Ox, Diclox

Gram positive (MSSA and Strep)

Natural penicillins

Pen G, Pen VK

Syphilus (Trep. Pal.) DOC

Gram Positive (Strep only)

Tetracyclines

2nd Generation
Tige, Omada, Erava

Gram negative (enteric)

1st Generation
Tetra, Doxy, Mino

Gram negative (non-enteric only)

Gram positive (MSSA, MRSA, Strep)

Macrolides

Azithromycin, Clarithromycin
Gram negative (enteric only)
Gram positive (strep)

Nucleic Acid Inhibitors

Fluoroquinolones
Delafloxacin

Anaerobes (oral, gut)

Gram negatives (incl. pseudomonas)

Gram positive (MSSA,MRSA + strep)

Levofloxacin

Gram negative (incl. pseudomonas)

Moxifloxacin

Anaerobes (Gut, oral)

Gram Negative (no pseudomonas)

Gram Positive (Strep)

Ciprofloxacin

Atypical

Aminoglycosides

Gentamicin, Tobramicin, Amikacin, Plazomicin
Gram positive (ONLY synergy)

Glycopeptides

Lipoglycopeptides
Vanc, Dapto, Telav, Dalba, Ortito

Gram Positive (MSSA, MRSA, Strep, Entero (except Dalba)

Listeria (Linezolid)

Folate Synthesis Inhibitors

Trimethoprim, Sulfamethoxazole
Gram Negative (variable)
Gram Positive (MSSA, MRSA, NO STREP)

Cell Membrane Inhibitors

Polymyxins
Gram Neg (only Pseudomonas)
Fosfomycin
Gram Negative (incl. pseudomonas)

Other

Nitrofurantoin
Gram negative
Gram positive (Enterococcus)
Metronidazole
Anaerobes (gut)

DOC B. Frag

Lefamulin
Atypicals
Gram Negative
Gram Positive (MSSA, MRSA, Strep)
Clindamycin
Anaerobes (oral)

NOT B. Frag

Gram Positive (MSSA, MSSE, MRSA(CA), Strep)