Pharmacodynamics

mechanisms of action

drug - receptor interactions

affinity

agonist

antagonist

drug - enzyme interactions

stimulation or blockage occurs

nonspecific drug interactions

drug - response relationships

efficacy

potency

serum concentration - time profile

onset of action or latent period

termination of action

duration of action

minimum effective concentration

peak serum concentration

toxic level

therapeutic range

adverse effects

good or bad

toxicity

allergic reaction

no safe drug

drug - drug interaction

synergism

chemical incompatibility

half - life elimination

50% of drug

therapeutic index

lethal dose

effective dose

TI = LD50 / ED50