UNIT 3:
Molecular Genetics

Scientists and their Experiments

1. Meischer

2. Levene

3. Griffith

4. Hammerling

5. Oswald, McLead, and McCarty

6. Chargaff

Subtopic

Subtopic

7. Hershey and Chase

Subtopic

Subtopic

8. Franklin and Wilkins

9. Watson and Crick

Control Mechanisms

The lac Operon

The trp Operon

The trp Operon

Genetic Technologies

Restriction Enzymes and Their Restriction Sites

EcoRI

EcoRI

BamHI

BamHI

SmaI

SmaI

HindIII

HindIII

AluI

AluI

HhaI

HhaI

Plasmid Map

Hybridization

Polymerize Chain Reaction

Gel Electrophoresis

Subtopic

Subtopic

Sequencing DNA

DNA Microarray

DNA Replication

How is DNA replicated?

Semiconservative

Semiconservative

Conservative

Conservative

Dispersive

Dispersive

Process of DNA Replication

Unwinding DNA

DNA Helicase, Single Stranded Binding Protein  DNA gyrase (topoisomerase)

DNA Helicase, Single Stranded Binding Protein DNA gyrase (topoisomerase)

Building Complimentary Strands

Leading and Lagging Strand

Leading and Lagging Strand

Replication Bubble

DNA Repair

Chromosome Structure and Organization

Structure of Chromosomes

Chromosomes

Chromosomes

Chromatin

Chromatin

Histone

Histone

Prokaryote DNA

Nucleotide and Plasmids

Nucleotide and Plasmids

Gene Organization In Chromosomes

Variable Number Tandem Repeats

Variable Number Tandem Repeats

Telomeres

Telomeres

Centromeres

Centromeres

Protein Synthesis

Transcription

Initiation

Initiation

Elongation

Elongation

Termination

Termination

Post-Transcriptional Modifications

Capping and Tailing

Capping and Tailing

Splicing

Splicing

Translation

Initiation

Initiation

Elongation

Elongation

Termination

Termination

What is Needed For Translation

Ribosomes

Ribosomes

tRNA

tRNA

Wobble Hypothesis

Wobble Hypothesis

Aminoacyl-tRNA synthesis

Aminoacyl-tRNA synthesis