Musculoskeletal System
Structure and function of the skeletal system
What is skeleton?
What are the types of bone?
cortical bone
Outer layer of compact layer
mechanical strength and makes up the majority of the skeleton.
cancellous bone
Inner, spongy layer of bone
contains a high number of bone cells and is responsible for changes in bone growth and structure.
bones vary in size and appearance
long
where is it usually found?
upper and lower
limbs, has a tubular shape with expanded ends.
the shape
e long cylindrical part,
and the expanded ends of the shaft are called the epiphyses. The center of the shaft is
hollowed out to form the marrow cavity, which is filled with fat and bone marrow.
purpose
provides considerable strength without excessive weight.
The parts of a typical long bone are referred to by specific terms.
short
where is it usually found?
include the carpal bones of the hands that allow movement of the wrist, and the tarsal bones of the feet that allow movement of the ankle.
the shape
shaped roughly as a cube and contain mostly spongy bone. The outside surface is comprised of a thin layer of compact bone.
purpose
provide stability to the wrist and ankle joints and also help facilitate some movements.
flat
where is it usually found?
occipital, parietal, frontal, nasal, lacrimal, vomer, hip bone (coxal bone), sternum, ribs, and scapulae
the shape
two thin layers of compact bone enclosing between them a variable quantity of cancellous bone, which is the location of red bone marrow.
purpose
protect internal organs such as the brain, heart, and pelvic organs.
irregular
where is it usually found?
vertebrae, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid.
the shape
vary in shape and structure and therefore do not fit into any other category. have a fairly complex shape, which helps protect internal organs
purpose
protect various parts of your body. Eg, your vertebrae protect your spinal cord.
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What are the cells that can be found in bones?
osteoblasts
definition
active bone-forming
cells that produce the collagenous bone matrix.
function/purpose
secrete an enzyme, alkaline phosphatase, that promotes deposition of calcium phosphate salts in the bone matrix to calcify the bone
relation with mitosis
Dont undergo mitosis
osteocytes
definition
Mature Osteoblast
function/purpose
Make the bone calefied and more rigid, osteoblasts
become incorporated within the bone and become transformed into relatively inactive mature bone cells called osteocytes.
relation with mitosis
Dont undergo mitosis
osteoclasts
definition
multinucleated cells related to
macrophages, are concerned with bone resorption.
function/purpose
They remove the bone matrix
by phagocytosis, dissolve the bone salts, and release the calcium and phosphate ions
into the circulation
relation with mitosis
Dont undergo mitosis
Strength and thickness of the bones
How do bone forms?
Intramembranous bone formation
Endochondral bone formation
Bone growth
How our bones are repaired?
Objectives
1. Structure and function of the skeletal system
2. Clinical manifestation of skeletal-related diseases
Clinical manifestation of skeletal-related diseases
Rickets
caused by
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manifestations
Delayed growth
Arthritis
one of the most common skeletal-related disease
3 common types
Rheumatoid arthritis
caused by
manifestations
Osteoarthritis
caused by
manifestations
Gout
caused by
manifestations
Bone fracture
caused by
manifestations
Osteoporosis
caused by
manifestations
stooped posture
Muscular dystrophy
caused by
manifestations
severe form
Team members
Omar Adel
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