Materiel and methods

New Zealand rabbits were anesthetized using intravenous injections

A 2 cm incision was made
approximately 1 cm below the lower edge of the mandible body to expose the bone.

A total of 29 rabbits were used for this experiment

20 rabbits were randomly divided into four groups
for radiographic and histological tests

the remaining nine rabbits were randomly divided into three groups for RNA-seq test: