Muscles
Protein synthesis
IGF1-Akt-mTor pathway
positive regulator
IGF-1
Pl3K
Akt
mTOR activity
muscle growth
muscle hypertrophy
Myostatin-Smad3 pathway
Follistation
muscle growth
negative regulator
mystatin actavin A
ACVR I/II
Smad 3 activity
mTOR activity
protein degradation
transcription factors
FOXO
Atrogin-1 activity
protein degradation
muscle atrophy
mTOR
protein synthesis
NF-kB
MuRF-1 activity
inflammatory cytokines
Structure
Epimysium
Perimysium
Endomysium
Single muscle fibers
Myofibril
Sarcomere
A band
Mysosin fillament
H band
I band
Z disc
Actin fillament
Stem cells
Satellite cells
Myonuclei in postnatal skeletal muscle tissue
Sarcolemma and basal lamina
Myoblasts
Muscle fiber
Other myoblasts
Myofibres
Dormant stage
Embryonic Myogenesis
Gastrulation
mesodermal layer
axial mesoderm
intermediate mesoderm
paraxial mesoderm
somites
sclerotomes
vertebrae and ribs
Dermomyotome
epaxial
muscle progenitor cells delamine from the edges of dermomyotome
Hypaxial
myotome
myoblast
myocyte
multinucleated muscle fiber
Subtopic
lateral plate mesoderm