Renal Failure

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Renal Failure

Main topic

Acute Renal Failure

Causes

Post-renal

Subtopic

BPH

Intra-renal

Microvascular disease (diabetes)

Amyloid

Protein deposition after inflammation - CONGO RED STAIN

Streptococcal infections

Immune complex deposition in small arteries - NECROSIS

Pyelonephritis

Fever, loin pain, rigors, pregnant (ureters dilate, more vulnerable)

Rhabdomyalysis (CK 600+)

Epileptic fits, lying on floor (fall), exercise, compartment syndrome, hyperthermia, statins

Nephrotoxic drugs

chemotherapy, gentamycin, ibuprofen

Glomerulonephritis

Pre-renal

Renal A. stenosis

Precipitated by ACEI/ARBs - start ACEI dose at night then check BP and 2 in 6 weeks + check U&Es

Hypovolaemia

Iatrogenic (anti-hypertensives)

Can lead to ATN