MALIGN AND BENIGN PATHOLOGIES IN BREAST
MAIN FINDINGS
Mammary duct ectasia
Intraductal papilloma
*Main cause of women who are not breastfeeding
*Bloody discharge
*Surgical removal of the duct
Purulent discharge from the nipple
*Infection
*Can produce an abcess
*Atibiotic treatment
Galactorrhea
*Involutive, bilateral, spontaneous, with pregnanciy and hipothyroidism
LUMP
A breast lump is a growth of tissue develops withing your breast. Different types of breast lumps can vary in the way they look and feel.
RISK FACTORS
family history
grandmother, mother, or sister
-Menopause
-Radiotherapy
Subtopicthe diet rich in fats and meats, as well as obesity, sedentary lifestyle and the consumption of tobacco and alcohol.
-Ductal hyperplasia
-Age
the use of hormone replacement therapies.
BREAST CANCER
DIANOSIS
IMAGING STUDY
*Biopsy
Breast biopsy is used to confirm or rule out breast cancer. It is done if other tests, such as a mammogram or a physical exam of the breasts, show that breast cancer might be present.
*Mammography
RRegular mammograms are the best tests doctors have to find breast cancer early. A mammogram is an X-ray image of the breast. Doctors use mammograms to look for signs of early breast cancer.
*Ultrasound
Breast ultrasound uses sound waves to produce pictures of the internal structures of the breast. It is primarily used to help diagnose breast lumps or other abnormalities found during a physical exam, or on a mammogram, or on an MRI of the breast.
*MRI
Breast MRI is a test used to detect breast cancer and other breast abnormalities. A breast MRI captures several images of the breasts. The breast MRI images are combined, using a computer, to create detailed images
BIOLOGICAL MARKERS
*Estrogen receptors
A breast cancer tumor is described as “estrogen receptor positive” if it has receptors for that hormone.
*Progesterone
Again, this means that cancer cells can receive signals from progesterone that stimulate their growth.
*Tumor size
Malignant (cancer): they grow rapidly and often metastasize, that is, they migrate to other parts of the body causing new tumors
p53
TP53 is a gene that helps stop tumors from growing. It is known as a tumor suppressor. A tumor suppressor works like the brakes on a car. Stops cells from dividing too quickly
*HER2/neu
Medir la cantidad del HER2/neu en algunos tipos de células cancerosas sirve para planificar el tratamiento. También se llama c-erbB-2, HER2, receptor 2 del EGF humano y receptor 2 del factor de crecimiento epidérmico humano.
*Axillary lymph node status
The lymph nodes are responsible for filtering lymphatic fluid and detecting chemical changes that indicate infection. When these filter points are in the armpit, doctors may call them axillary lymph nodes.
GALACTOCELE
*Thick milky liquid
*Condensed
*Painful breast cyst
BENIGN ALTERATIONS
ADENOMA
-Scattered stroma
-Peak incidence at 20-30 years
-Circumscribed tumors
LIPOMA
*Most common non-epithelial neoplasm
*Fatty
*Mobile
*White tummor
MASTITIS
- May appear in puerperal phenomena
-Sthapylococcus aureus
- Related to lactation factors
DUCTAL ECTASY
* Small abscess at the base of the nipple
*Perimenopause and postmenopause
*Hard and tender erythematous mass
Phylloid tumor
- Total surgical diagnosys
- Any age
Slow-growing epithelial neoplasia
PLOTIFERATIVE ALTERATIONS
*Hyperplasia
*Adenosis
*Seropurulent exudate
*Athypical dictated epithelium
FIBROCYSTIC ALTERATIONS
-Edema
- Pain
-More common
-Premenopause
MASTOPATY
-Is associated with pregnancy, lctation, trauma and thrombophlebitis
-In reproductive stage
SELF-EXAMINATION
Questioning and physical examination
Palpation, inspection