Systemic inflammatory response syndrome (SIRS)

a

CRITERIA (When any 2 or more of these are observed at a time SIRS is confirmed)

Respiratory rate >20 breaths per minute or PaCO2 <32 mm Hg

Abnormal white blood cell count (>12,000/mm3 or <4,000/ mm3 or >10% bands

Fever >38◦C or < 36◦C

Heart rate >90 beats per minute

PATHOGENESIS

Preoperative Illness

Trauma or Operation

Tissue Ingury

Optimal Oxygen Therapy

Recovery

Inadequate Resuscitation

SIRS/MOD

Excessive Inflammatory Response

SIRS/MOD

ETIOLOGY

Ischemia

Inflammation

Trauma

Infection

Combination of several “insults"