ACE Inhibitor
Renal Scintigraphy
Radiopharmaceuticals
99mTC-DTPA
1-10mCi
(1mCi if doing
1day baseline
study)
99mTc-MAG3
1-10 mCi
Captopril
25-50mg taken orally
imaging begins 1 hour after
Analysis
Normal Study:
RPH should wash out
regardless of ACE
inhibitor
Abnormal Study:
Lingering Uptake after
administration of ACE
inhibitor
RPH not washing out
Imaging Techniques
Image Posterior
Patient Supine
Kidneys near top of FOV
Instrumentation
LFOV
LEHR
Dynamic/Flow
128x128 matrix
Critical Organ
Bladder wall
Indications
Renal Hypertension
Contraindications
Pregnant/Breastfeeding
Patient Motion
Imaging Protocol
Flow
1-3 sec/frame->30frames
Dynamic
10-30 sec/frame->30minutes
Post-void
500k counts
Upright
Patient Prep
ACE Inhibitors should
be held
Captopril
48 hrs
Enaliprat/Lisinopril
1 week
NPO 4 hrs
Pt should be well hydrated
Optional manuevers
2 day study may be employed
If ACE Inhibited Study
is abnormal, basline
may be performed next
day
If it is normal,
then no baseline
is necessary