Protozoa
Encystement
protective capsule called cyst
cyst allows parasitic species to live outside of hose
oocyst: phylum Apicomplexa--cells produce asexually
Life Cycle
asexually by fission, budding or schiogony
schizogony: multiple fission, nucleus undergoes division before cell divides--cyto surrounds the many nuclei then separates
sexual by conjugation: two cells fuse and haploid nucleus from each cell migrate to the other cell. Haploid micronuclei fuse and parent cells separate each now a fertilized cell
some form gametes
General info
unicellular
eukaryotic
chemoheterotrophs
water and soil
trophozite: feeing and growing stage--feed upon bacteria and small particles
normal microbiota of animals
few cause human disease
malaria 4th leading cause of death
Medically Important Phlya of Protozoa
Archaezoa
eukaryotes that lack mitochondria
mitosomes instead
symbiontsi n animals
spindle-shaped with front end flagella
Subtopic
Trichomonas vaginalis: human parasite
undulating membrane: membrane bordered by flagellum
Giardia lamblia: small intestine--excreted in feces as cysts--giardiasis
Microspora
eukaryotes that lack mitochondria
no microtubules
obligate intercellular parasites
Amoebozoa
move by extending pseudopods
Entamoeba histolytica: only path. amoeba in humans
lectins attach to galactose on PM and cause cell lysis
E. dispar: nonpath in human and is most common
Acanthamoeba: in water can cause blindness
Balamuthia: brain abcesses
Apicomplexa
nonmotile in mature form
obligate intracellular parasites
complex of special organelles at tip that penetrate host
Plasmodium: malaria
sexual reproduction in Anopheles mosquito
1. sporozite (infect stage) injected into human and carried to liver
2. undergo schizogony in liver cells and produce progeny called merozoites
3. merozoites enter bloodstream and infect red blood cells
4. young trophozoite look like a ring in which the nucleus and cyto are visible--ring stage
5. ring stage enlarges and divides repeatedly
6. red blood cells rupture and release merozites...waste products that cause fever are released
7. picked up by bite of another mosquito---enter mos. intestine and begin sexual cycle
male and female gametocytes join to form zygote--oocyte formed--divides into asexual sporozoites
8. oocytes rupture and send sporozoites to mosquitos saliva---then they bite a human
mosquito--definitive host--where sexual stage occurs
human--intermediate host--where asexual stage occurs
Babesia microti
red blood cell parasite
fever and anemia in immunosuppressed
transmitted by tick
Tocoplasma gondii
human parasite from domestic cats
trophozoites--called tachyzoites repro sexually and asexually in cat--oocytes w/sporozoites excreted
congenital defects in uetero
Chryptosporidium
human parasite
respiratory and gall bladder infections
Ciliophora
ciliates--cilia arranged in precise rows
Balantidium
human parasite (only ciliated one)
causes severe dysentry
cysts are ingested by host and enter large intestine
Alveolata
ciliates, apicomplexans, and dinoflagellates may be placed here
they all have membrane-bound cavities under the cell surface
same rRna sequences
not sure why this info goes here...
Euglenozoa
Euglenoids
photoautotrophs
pellicle
move by flagellum at anterior end
red eye spot to sense light
some are facultative chemoheterotrophs
can photosynthesize
hemoflagellates
blood parasites
long slender bodies with undulating membrane
Trypansoma: African Sleeping sickness
T. brucei gambiense: tsetse fly transmission
T. cruzi: Chagas' Disease--"kissing bug" b/c is bites on face
Nutrition
mostly aerobic heterotrophs
in intestines anaerobic growth
need lots of water
pellicle--special covering
ciliates wave food to special opening called cytosome
amoebas phagocytize and digestion is in vacoules--waste out thru anal pore or PM