TRH neuron

r

Options:

Releases TRH to the Pituitary thyrotrope cell

Pituitary thyrotrope cell

Pituitary thyrotrope cell
Thyroid epithelial cell

Thyroid epithelial cell

Contains TRH receptor

Ca2+ and PKC stimulate THS synthesis and secretion

Hypothalamus

Pituitary

Pituitary thyrotrope cell

Pituitary thyrotrope cell
Thyroid epithelial cell

Thyroid epithelial cell

Thyroid

****Insert image of thyroid epithelial cell ***

T3

Brain

Bone

Heart

Metabolic responses

TRH Neuron

Stimulates Ca2+ and PKC

TSH Synthesis and secretion

TSH Receptor on Thyroid

Stimulates PKC

All aspects of thyroid hormone synthesis and secretion as well as cell growth

T4

Skeletal Muscle

Auditory

Liver

TRH Receptor on Pitutary