EFFECT OF FREE RADICALS

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Introduction

par Mohammed H.

Why are historical influences important in molecular genetics?

par Erin Truong

Organigram

par Peace Tolulope Ogedengbe

Historical timeline of Microbiology

par Michelle Chin

EFFECT OF FREE RADICALS

PTN cross linking

cystine - lysine - methionine - histidine

enzyme inactivation :Sulfa-hydral enzyme

DNA damage

3- Mutations or cell Killing

2- single strand DNA

1- free radical with thymine =Oxidation

Non-peroxidative mito mem damage

Fenton reaction

Xanthene oxidase

lipid peroxidation of Membranes

free radical attach to double bond of mem form : Lipid peroxide

this LIPID peroxide: unstable & Reactive= extensive damage to All membranes