Nervous System

5 Characteristics of Neurons

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Also study:12 Cranial Nervesnerve impulse physiologynerve impulse/action potentialevents leading to the release of a neurotransmittercomparison of somatic & autonomic nervous systemsspecial senses

extreme longevity - lives a long time(your life span)

amniotic - do not divide; won't be replaced

high metabolic rate - chemical reations are happening very quickly

excitable - sensitive to changes in environment and pH is relevant(acidosis depresses, alkalosis excites)

conductivity - transmits impulses from one nerve to another

Myelin Formation

made up of phospholipids(fat) - protein and cholesterol

myelinated axons - white matter unmyelinated axons - grey matter

all Schwann cells together form myelin

node of Ranvier (ron-vee-ay) - important when transmitting & conducting impulses along the axon

Nervous Tissue

neuron - entire (single) cell

neuroglia - netted support tissue for neuron

located in spinal cord, brain, and nerves (these are made up of nervous tissue)

2 Divisions

Central Nervous System (CNS)

brain

spinal cord

Peripheral Nervous System (PNS)

all other nerves

12 pairs of cranial nerves

spinal nerves

sensory division - input of receptors

motor division - somatic and autonomic nervous systems

Nerve Structure

nerve cell connected to nerve by axon

connected to axon is the endoneurium

wrapping around endoneurium is the perineuium

surrounding the perineuium is many fasicles

wrapping around the entire structure is the epineurium

5 Types of Neuroglia

1. Microglial - CNS; phagocytize(eat) cell bacteria & cell debris; numbers of these will increase when infection arises

2. Oligodendrocytes - CNS; form myelin in CNS; wherever they are, there is also white matter; without them, there is gray matter in CNS

3. Astrocytes - CNS; star-shaped, large cells with processes that come in contact with blood capillaries & neuron; handle exchange/transport of substances between blood & neuron

4. Ependymal - CNS; in fluid-filled cavities of brain are ventricles, in spinal cord is central canal; controls composition of this fluid & circulate the cerebrospinal fluid

5. Schwann - PNS; only cell of Perioheral Nervous System

Cerebrospinal Fluid

clear, viscous(thick) fluid secreted by choroid plexus into subarachnoid space

functions: maintain stable ionic concentrations for CNS; protective cushion

secretes 500 ml; only 140 ml present in a day, rest of it goes to sinuses

spinal tap/lumbar puncture - between L3 and L4 vertebrae(below spinal cord); goes into subarachnoid space and examines fluid for infection

hydrocephaly - "water on the brain"; fontanel membrane has not ossified * so it keeps stretching to fit the liquid and head is very large; fluid must be removed by channeling the fluid out and into a tube in the neck

Reflex Arc

direct route from sensory nueron to effectors(always travels the same path); rapid, predictable, involuntary response

example: hitting the patellar ligament on knee; simplest of all reflexes, same thing happens everytime, same action that cannot be controlled

ex: feel something burning, pulls hand away asap

ex: step on a tac, lifts foot immediately

Ventricles & Location of Cerebro Spinal Fluid

4 ventricles(fluid-filled sacs with CSF) in brain

location: ventricles, central canal(SC), & subarachnoid space

Spinal Cord

from foramen magnum to vertebral foramen

2 functions: spinal reflexes; conduct ascending(sensory) -posterior entry is also sensory; descending tracts(motor) - anterior exit is also motor

nerves - only in PNS, not in brain or spinal cord vs. tracts - only in CNS

ganglion - clusters of cell bodies(neurons) forms swollen area on dorsal in PNS vs. nuclei - clusters of cell bodies in CNS

Meninges

meninges - protective covering for brain and spinal cord

meningitis - inflamation of meninges

looks like a sac that covers brain & ic connected to bone & christa galli

outside part of meninges is called Dura Mater(outermost layer of meninges under subdural space); closest to skull

Arachnoid Mater - 2nd, mid layer; web-like, thin like a spider web, beneath is subarachnoid space with CSF circulating

innermost layer of meninges is Pia Mater; covers brain like shrink wrap in all sulcus & sulci; contains blood capillaries known as choroid plexus that make cerebrospinal fluid that circulates above the Pia Mater; closest to brain

transverse & sagittal sinus that are flattened blood vessels

Spinal Cord: meninges are in the same order except there is an epidural space between the bone & Dura Mater with blood vessels running through it(where epidurals are administered)

Functional Classification of Neurons

sensory(afferent) - approaching, entering; goes into back of spinal cord(dorsal)

interneuron - between sensory & motor neurons; totally enclosed in CNS; routes impulses where they need to go

motor(efferent) - outward, away; exciting; ventral, comes out front of spinal cord

Neuron Structure

dendrites - recieving portion(impulses from other neurons) are seen as projections off of cell body

cell body - has typical cell structures

axon - connects cell body to axon terminals(with synaptic vesicles inside); carries impulses away from cell body to axon terminals

Schwann cell - type of neuroglia(only found in PNS - Peripheral Nervous System)