Cardiovascular Drugs

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Chapter 25

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Cardiovascular Drugs

AntiAngina

Diltiazem/Cardizem

- Dromotropic

- Inotropic

- Chronotropic

Decreases Angina from coronary artery spasm

lowers HR in A-fib or flutter

Calcium Channel Blocker

Beta Blockers

Nonselective not for COPD or asthma

Lower contractibility

Lower HR

Nitroglycerine/Nitrostat

Cardiac and BP monitoring + Call MD if Systolic < 90

Viagra + Nitro = VERY BAD DAY

Decreases workload

Reduces preload

Dilates Blood vessels

For Angina

Pipes (Blood Vessels)

Plasma (Blood Volume)

Diuretics

Mannitol/Osmitrol

ICP

filter needle, keep warm r\t crystals

Osmotic

Lower fluid levels FAST

EMERGENCY DRUG

Spironolactone/Aldactone (ATI)

Collecting tubial

Triamterene/Dyrenium

Weak

Collecting Tubial

Potassium Sparing

Hydrochlorothiazide/Diuril

2 Hours

Na, Cl, H2O excretion @ distal tubial

For HTN and Peripheral Edema

Furosemide/Lasix

Na, H2O excretion at loop

HTN, Edema, renal disease

Can increase renal blood flow 40%

fast action

High Ceiling Diruetic

Pump (Cardiac Contraction)

Antidysrhythmics

IV Calcium Channel Blockers

Diltiazem/Cardizem, Verapamil/Calan

Atrial Fib and Flutter

slows conduction

increase refractory period of AV node

Decrease excitability and contractility of myocardium

III  Prolong Repolarization

Amiodarone/Cordarone  (one)

prolongs action potential

increases refractory period

Emergency treatment of V-fib and V arrhythmias

II  Beta Blockers (lol)

Acebutolol (Sectral), Metoprolol (Lopressor), Propranolol (Inderal) (non-selective)

Blocks Beta-1 (antagonist)

High BP

Angina

Dysrhythmias (especially Ventricular)

Block effect Catecholamines

Slow heart rate

I  Fast sodium channel blockers A,B,C

C. No Prototype

Suppress PVC

B. Lidocain/Xylocain

raises ventricular firing threshold

Prolongs repolarization

Slows conduction

A. Procainamide/Pronestyl & quinidine

Lessens likelihood of ectopic beats

increases time for repolarization

decreases conduction velocity & automaticity

Cardiac Glycocides

Dobutamine/Dobutrex

Emergency Drug

Monitor BP and Heart

+inotropic, CHF

+ Beta 1 agonist

Digoxin/Lanoxin

Antidote Digibind

- dromotropic

- chronotropic

+ Inotropic