a Jenny Doriot 16 éve
355
Viruses and Cancer
Research into the connection between viruses and cancer has revealed significant findings. Early discoveries in mice showed virus-induced adenocarcinomas, and subsequent studies identified DNA oncogenic viruses like Epstein-Barr virus, human papillomavirus, and hepatitis B as contributors.
Megnyitás
Viruses and Cancer RNA Oncogenic Viruses Subtopic human T-cell leukemia only from family Retroviridae DNA Oncogenic Viruses hepatitis B Epstein-Barr virus human papillomavirus Transformation of Normal Cells into Tumor Cells less round than normal cells and show abnormalities T antigen...antigen in nucleus of tumor cell tumor specific transplantation antigen...antigen on cell surface tumor cells undergo transformation oncogenic viruses: 10% of cancers Bishop and Varmus: Nobel 1989..cancer-inducing genes carried by viruses are actually derived from animal cells affect parts of the genome called oncogenes Unrecognized because: cancers are not contagious like viral diseases usually are cancer may not develop until long after infection most of the particles infect cells but do not induce cancer adenocarcinomas in mice were discovered in 1936...virus-induced Sarah Stewart..discovered and isolated human cancer-causing virus first demonstrated in 1908 by Wilhelm Ellermand and Olaf Bang...causative agent of chicken leukemia F Peyton Rous...chicken sarcoma