Biology: Concept Map
Protein Traffic
Plasma Membrane
Exocytosis
Rough ER
Lumin
Plasma membrane contains
SRP Receptor
binds to the
SRP protien
Are found in
Cytosol
binds to
Protiens
Contain
ER Sequence
to synthesize
RNA
use
Ribosomes
Protein undergoes glycosylation
Adds a carbohydrate group
Forms a glycoprotein
Which through a vesicle to the
Golgi Apparatus
Which has a cis face
Protein then travels with cisternae
Is a specific vesicle
To the trans face
Protein exits and travels with a vesicle
Has a specific "tag"
Directed to the cytoplasm using a motor protein
Travels on microtubles
Arrives at the
Cell Signaling
Local Signaling
Short Distance
3 Steps
Reception
Targets
Cell Detections
Transduction
2 Types
Series of Change
Single Step
Response
Triggers
Specific cellular response
Regulates
Cell Metabolism
Cytoplasmic Activity
Nuclear transcription
Synoptic neuro transmitters
Paracrine (growth Factor)
Binds with
Signal Molecule
Ligand
Long Distance Signaling
Horomones
Protein Phosphorylation
Protein Kinase
Reversal Enzymes
Protein Phosphotases
Phosphate
from ATP
Protiens
Activates
Protiens
Cell Reproduction
Ion Channels
Ligand Gated
allows
Calcium Ions
Into
Cytoplasm
From
Mitochondrial Matrix
Second Messangers
Non protien signaling pathway
Example
Cyclic AMP (cAMP)
Example
Glycogen breakdown with epinephrine
Enzyme
G-Protien linked receptor(in membrane)
Created
Adenylyl Cyclase
Gene Expression
Replication
uses enzymes and proteins
DNA helicase
unzips DNA helix
Replication fork is formed
forming leading strand
strand is continuously synthesized
by DNA polymerase
RNA primase synthesizes RNA primer
lagging strand
discontinuously synthesised
RNA primase creates
RNA primer
DNA polymerase replicates primer
Okazaki fragments are linked
By
DNA Ligase
Topoisomerase
Prevents DNA from recoiling
DNA polymerase
adds nucleotides
in 5'->3' direction
SSB
Keeps DNA strands separated
Primase
Synthesizes short RNA primers
Starting point for DNA synthesis
Transcription
Occurs in nucleus
starts with DNA
unzipped by RNA polymerase
Creates mRNA
Translation
Occurs in cytoplasm
Begins with mRNA
Contains codons
Binds to anti codon
Contains tRNA
Can fit two ribosomes
contains amino acids
make protein