Introduction To Biochemistry

Intermolecular Forces

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The force that mediates interactions between bonds

London Dispersion Forces (Van Der Waals Forces )

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A slight attraction develops between the oppositely charged regions between nearby regionsSame as London Dispersion Forces

Hydrogen Bonds

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A strong inter molecular force of attraction between a partially positive hydrogen and a partially negative Oxygen , Nitrogen , or Fluorine ( HNOF )

Dipole-Dipole Forces

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Forces between polar molecules , opposite poles match up by electrostatic attraction

Ion-Dipole Forces

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Forces between a polar molecule and a non polar molecule

Carbohydrates

Essential Nutirenst

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Nutrients we need in order to survive

Monomers

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Molecules that bond together in order to make more complex structures i.e polymers

Polymers

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A structure of molecules made by smaller molecules called Monomers

Glycosdic Linkage

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A chemical Bond that forms between two Monoasccharides in a Condensation Reaction

Disaccharides

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-

Oligosaccharides

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Polysaccharides

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Starch - a Branch Polysaccharide found in plants, made up of amylose and amylopectinAmylose - made up of glucose molecules chainAmylopectin - a branch chain of glucose with a 1,4 and 1,6 glycosidic linkages

Macronutrients

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Molecules that livings things need in a relatively large amount to live

Monosaccharides

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The Monomers of CarbohydratesContains Hydroxyl and Carbonyl Groups

Aldose and Ketose

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Aldose and Ketose are both Monosaccharides

Isomers

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Molecules with the same number and type of atoms , but arranged differently

Proteins

Amino acids and Essential Amino Acids

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Amino Acids are the monomer of protein ,made up of a amine and carboxyl group , with a central carbon with a h and r groupEssential Amino Acids are acids we need to obtain our diet because we don't have metabolic processes to process them

R-groups

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the unique portion of amino acids that defines its properties

Peptides/Polypeptides

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Peptides - a short chain of amino acidsPolypeptides - a complex structure of amino acids made by peptides

Primary,Secondary,Tertiary,Quaternary Structures

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Primary (a) - the sequence of amino acidsSecondary ( b ) - The localized structure as to whether or not the amino acid sequence forms a alpha-a-helix or beta-b-pleated based on hydrogen bondingTertiary ( c ) - a 3D structure based on other intermolecular forces including ionic bonds , hydrogen bonds , disulfide bridges , and hydrophobic interactionsQuaternary ( d ) - a 3D structure where more than one polypeptide chain is involved

Hydrophobic/philic

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phobic - fear of waterphilic - attract to water

Lipids

Fatty acids

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Long Hydrocarbon Chains that end in a carboxyl groups the carbon chains can be un/saturated or have single/double bonds

Glycerol

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       a 3 carbon molecule with 3 hydroxyl groups

Waxes

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Are Waterproofing LayersOnly expeirence L.D.FLong , Straight Chains

Amphipathic

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have both polar/non-polar regionsmostly hydrophobic

Micelle

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An Amphipathic Lipid

Bilayer

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A double layer of closely-packed lipids

Triglyceride

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they function as long term energy storage moleculesthe carbon chains are a source of carbon to enter the Krebs cycle producing NADH for the electron transport chain

Phospholipids

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Make up majority of the Cell Membrane They consist of a hydrophobic head , made up of a polar group, a phosphate group , glycerol , and a hydrophobic fatty acid

Steroids

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They function a signaling molecules and components of the cell membraneTestosterone , estradiol , and progesterone are hormones involved in the reporductive system only experience L.D.F, non-polar , hydrophobic , and insoluble

Mosaic

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Cell Membrane is made up of :Phospholipids Integral proteins Peripheral proteinsChannel ProteinsAlpha-Helix proteinsglobular proteinsGlycolipidsGlycoproteinsCholesterol

Glycolipid/protein

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a lipid/protein with a carbohydrate added to it

Transmembrane Protein

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a integral protein that spans the entirety of the cell membrane

Nucleaic Acid

Nucleotide

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the building blocks/monomers of Nucleaic Acids

Phosphodiester Bond

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a phosphate with 4 oxygens , on of them is double-bondMakes up ATP

Nitrogenous Base

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Adenine PurineMakes up ATP

Ribose/Deoxyribose

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Both are Pyrimidinesboth have a 5' and 3' carbon The difference is ribose has a hydroxyl functional group on the 2' carbon, but deoxyribose does not

ATP

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Adenosine Triphosphate, a NucleotideMade up of a Phosphate group , a sugar ( ribose ) , and a Nitrogenous Base ( adenine )

NAD+/NAPD+/FAD+

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NAD+ consist of 2 phosphate group, 2 sugar ( ribose ) , and 2 nitrogenous base ( 1 adenine , 1 cytosine ) NADP+ consist of 3 phosphate group , 2 sugar ( ribose ) , and 2 nitrogenous base ( 1 adenine , 1 cytosine ) FAD+ consist of 2 phosphate group , 2 sugar ( 2 ribose ) , 2 nitrogenous base ( 1 adenine , 1 Guanine )

Autotrophs/Heterotrophs

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Autotrophs are able to make their own food using raw materials / energy ( producers )Heterotrophs must consume other organisms in order to get food ( consumers )

Double Helix

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a DNA strand is made of of two linked strand that wrap around each other , resembling a twisting ladder ( helix shape )

Potential energy

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energy that has the potential to become another form of energy

Independent/Dependent, and Controlled Variables

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Independent - the variable that is altered during a scientific expiriment Dependent - the variable being tested or measured Controlled - a variable that stays the same

Fair Test

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A test that controls all but one variable when trying to answer a question

Neurotransmitter

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Chemical Messengers their job is to carry chemical signals from one neuron to another

Hormones

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Chemical messengers that coordinate different functions in your body

Intramolecular Forces

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Forces within molecules that hold atoms together

Ionic Bonding

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A metal loses a electron, becomes a +ve cation, to a nonmetal, that gains a electrons becomes a -ve anion-ve and +ve are electrostatically attracted

Non-polar/Polar

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Two non-metals share electrons equally Two non-metals share electrons unequally

Covalent Bonding

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The sharing of electrons between Atoms

Biochemical Reactions and Functional Groups

Hydroxyl Group

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R-----O-----HPolar HydrophilicCharacterized by presences of H and O

Sulfhydryl Groups

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R-----S-----HPolar HydrophilicCharacterized by presence of S

Carbonyl Group

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O ll llR-----C-----RPolar Hydrophilic Characterized by central C and O Bound to two side groups Double bond to oxygen increases the polarity

Phosphate group

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Acidic Polar HydrophilicCharacterized by presence of P

Aldehyde

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Polar HydrophilicCharacterized by Central C and OBound to 1 side groups Double bond to oxygen increase the polarity

Ketones

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Polar Hydrophilic Characterized by Central C and OBound to 2 side group Double bond to oxygen increases polarity

Enzymes

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Acts as a Catalyst during chemical reactions

Reactants

Product

Catabolic

Hydrolysis Reactions

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AB + H20 --> A + BExample of A Catabolic Reaction 

Glycosidic

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In a saccharide , both the Ribose and Deoxyribose are bonded by a single oxygen , which is called the Glycosidic reaction

Anabolic

Condensation Reaction

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( I tried to put and image here but it didn't work )A + B --> AB + H2OExample of an Anabolic reaction

Redox reaction

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Add Oxygen is oxidationLose Hydrogen is oxidationGains hydrogen is reduced Remove oxygen is reducedRH2 + B -> R + BH2

Phosphorylation

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Phosphorylation:R +ATP -> R-PO4 + ADP

Neutralization

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A Neutralization reaction occurs when a acid and base react to create a water and a saltex.HCL + NaOH = NaCl + H2O

Isomerzation

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AB<->BA

Ester/Amide/Phosphodiester

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Ester - a organic compound where the hydrogen in a carboxyl group is replaced with a hydrocarbon groupAmide - an organic compound that contains a functional acyl group ( R-C=O ) linked to a nitrogen atomPhosphodiester - the linkage between the 3' carbon of one sugar molecule and the 5' carbon of another

Ester Linkages

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Triglyceride and Phospholipids are formed by condensation reactions and broken apart by Hydrolysis reactionsthe hydroxyl group with glycerol reacts with carboxylic acid of the fatty acids to form a ester linkages

Intermolecular Forces of Attraction

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A attractive force between a positive component and a negative component of molecules