Nucleic Acid Research database

Organization of databases and its major grouping

Nucleic Acid Research database

Nucleotide Sequence Databases

RNA sequence databases

Protein sequence databases

General sequence databases

CharProtDB

COMBREX

EXProt

MIPS resources

NCBI Protein database

PA-GOSUB

PIR - Protein Information Resource

UniProt

Protein properties

BindingDB

AAindex

PFD - Protein Folding Database

Protein domain databases; protein classification

3DSwap: Database of Proteins involved in 3D domain Swapping

ADDA - A Domain Database

DomIns - Database of Domain Insertions

Databases of individual protein families

Aminoacyl-tRNA synthetase database

ChromDB

Death Domain database

Nuclear Receptor Resource

Structure Databases

Genomics Databases (non-vertebrate)

Metabolic and Signaling Pathways

Human and other Vertebrate Genomes

Human Genes and Diseases

Microarray Data and other Gene Expression Databases

Proteomics Resources

Other Molecular Biology Databases

BioModels

BioNumbers

GeMInA

Subtopic

Why these databases are useful in describing our chosen protein

Brenda

we can know about biochemical and molecular information on classification and nomenclature, reaction and specificity, functional parameters, occurrence, lipase structure, application, engineering, stability, disease, isolation and preparation, links and literature references

HGMD

can study the mutational mechanisms in human genes

SFLD

get know how conserved residues map to catalysis of partial reactions or other shared functions at a finer level of detail than overall reactions

NCBI

view and search an organism's complete genome, display chromosome maps, and zoom into progressively greater levels of detail, down to the sequence data for a region of interest

KEGG

presents a comprehensive set of metabolic pathway charts, both general and specific, for each of the sequenced genomes

UniProt

provide the scientific community with a comprehensive, high-quality and freely accessible resource of lipase protein sequence and functional information

iPfam

enable us to look at the conservation of domain–domain interactions between different PDB entries lipase

PDB

can study the structures of biological macromolecules and their relationships to sequence, function, and disease through different resources and tools

Databases used in assignments

BRENDA

Collection of enzyme functional data, which are classified according to Enzyme Commission list

HGMD

Human Gene Mutation Database; unique resource providing data on human inherited disease mutation to genetics and genomic research

SFLD

Structure-Function Linkage Database classifies enzymes related to specific sequence-structures features to their chemical capabilities

sfld.rbvi.ucsf.edu/django/web/about/

NCBI

The National Center for Biotechnology Information providing access to biomedical and genomic informartion

KEGG

A database for understanding high level functions of molecular biology, especially datasets generated from genome sequencing and experimental data

UniProt

Provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information

iPfam

Provides a catalogue of protein family interactions, calculated from known structures

RCSB PDB

Providing an information about the 3D structures of large biological molecules, including proteins and nucleic acids

Group Members

Nurul Syahirah binti Mohd Nasir

Siti Maysarah binti Abd Rahim

Nor Afrah binti Ahmad Tarmezi

Nadia Hakim binti Nasseri

New Yen Khim