Eicosanoids

Immunity

Inhibition of platelet aggregation

Stimulation of Platelet aggregation

Leukocyte Chemotaxis

Not Stored in Cells

Signaling Molecules

20 Carbon Essential Fatty Acids

Omega 3

5 Double Bonds

Omega 6

4 Double Bonds

Proinflammatory

Dihomo-gammi-linolenic Acid

3 Double Bonds

Inflammation

Asprin/NSAIDS

Down regulation of
eicosanoid synthesis

TWO ENZYMES

PROSTANOIDS

Promotion sleep,
fever
heat
Inducing Pain
inhibiting pain
swelling

Leukotrienes

Chemotaxis of leukocytes

Eicosa (Greek) - Twenty