pharmacodynamics

The classification of drugs

Agonist

Partial Agonist

Receptor Classification

transmembrane receptors

Membrane receptors transmit information about extracellular stimuli into the cytoplasm. This is achieved through a combination of changes in conformation and oligomeric state by membrane proteins with a single transmembrane domain

enzyme receptors

situated on enzymes the function of which is inhibited when a drug binds to them

transport-carrier receptors

situated on carriers in cell membrans and can be utilised by certain drugs to carry them across the cell membrane

storage receptors

present in nerve endings in which endogenous neurotransmitters are stored

plasma-protein receptors

situated on plasma proteins. most drugs bind to plasma proteins

Difference between Pharmacokinetics and Pharmacodynamics

Pharmacokinetics

Describes the effect the body has when a drug is administered

Parmacodynamics

Pharmacological effect on the body from the drug administered

summary of the factors that determine the therapeutic and/or side effect of drugs

side effect Type of drug
Quantity of drug used
Method of drug use
Time taken to consume
Tolerance
Gender, size and amount of muscle
Use of other psycho-active drugs
Mood or attitude
Expectation
Setting or environment effects

therapuetic identified include: route of administration, treatment complexity, duration of treatment period, medication side effects, degree of behavioral change required, taste of medication requirement for drug storage

secondary pathway receptors

alpha receptor

any of a group of receptors that are present on cell surfaces of some effector organs and tissues innervated by the sympathetic nervous system and that mediate certain physiological responses when bound by specific adrenergic agents

oxymetazoline

beta receptor

any of a group of receptors that are present on cell surfaces of some effector organs and tissues innervated by the sympathetic nervous system and that mediate certain physiological responses when bound by specific adrenergic agents

Beta-1 receptor

Receptors can be activated by either endogenous agonists (such as hormones and neurotransmitters) or exogenous agonists (such as drugs), resulting in a biological response.

are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist