pharmacodynamics
The classification of drugs
Agonist
Partial Agonist
Receptor Classification
transmembrane receptors
Membrane receptors transmit information about extracellular stimuli into the cytoplasm. This is achieved through a combination of changes in conformation and oligomeric state by membrane proteins with a single transmembrane domain
enzyme receptors
situated on enzymes the function of which is inhibited when a drug binds to them
transport-carrier receptors
situated on carriers in cell membrans and can be utilised by certain drugs to carry them across the cell membrane
storage receptors
present in nerve endings in which endogenous neurotransmitters are stored
plasma-protein receptors
situated on plasma proteins. most drugs bind to plasma proteins
Difference between Pharmacokinetics and Pharmacodynamics
Pharmacokinetics
Describes the effect the body has when a drug is administered
Parmacodynamics
Pharmacological effect on the body from the drug administered
summary of the factors that determine the therapeutic and/or side effect of drugs
side effect Type of drug
Quantity of drug used
Method of drug use
Time taken to consume
Tolerance
Gender, size and amount of muscle
Use of other psycho-active drugs
Mood or attitude
Expectation
Setting or environment effects
therapuetic identified include: route of administration, treatment complexity, duration of treatment period, medication side effects, degree of behavioral change required, taste of medication requirement for drug storage
secondary pathway receptors
alpha receptor
any of a group of receptors that are present on cell surfaces of some effector organs and tissues innervated by the sympathetic nervous system and that mediate certain physiological responses when bound by specific adrenergic agents
oxymetazoline
beta receptor
any of a group of receptors that are present on cell surfaces of some effector organs and tissues innervated by the sympathetic nervous system and that mediate certain physiological responses when bound by specific adrenergic agents
Beta-1 receptor