Reduction of ketone

- acylation and purification

- LDA synthesis and actual rearrangement

ester hydrolysis

- purification

- cyclization of (alkyl) carboxylic acid to alkylated cyclic ketone

- purification

- purification

- rearrangement

- purification

- reduction of aldehyde with NaBH4

- cyclization of second OH to lactone

- purification

- synthesis of Grignard-reagent

- treatment with Grignard-reagent of aldehyde

- cyclization of product to alkyl-laktone

- purification

- rearrangement

- purification

- cyclization of carboxylic acid to cyclic ketone

- purification