Rearrangements

もっと見る

macromolecules by chloe sharp

Chloe sharpにより

SYNTHESIS

Laura Jimenezにより

Endoplasmic Reticulum

Sarah Chapmanにより

Black Shoe Lace

Noah Boccongelleにより

Reduction of ketone

Johnson

- cyclization of carboxylic acid to cyclic ketone

Saucy-Marbet

- rearrangement

- synthesis of Grignard-reagent

- treatment with Grignard-reagent of aldehyde

- cyclization of product to alkyl-laktone

- reduction of aldehyde with NaBH4

- cyclization of second OH to lactone

Ireland

- acylation and purification

- LDA synthesis and actual rearrangement

- purification

- cyclization of (alkyl) carboxylic acid to alkylated cyclic ketone

ester hydrolysis