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It is related
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Caused
Presents
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In

ASTHMA

Respiratory System

Chronic inflation of air routes

Allergies, Physical Exercise,
Pharmacos, Environment and
Emotions

Increase in bronchial response

Wheezing, Shortness of breath, Intercostal Run,Tos and Chest tightness

Autonomic Immune System and Nervous System

Multifactorial Etiology

Children with family history of major allergy triggers

Types of Asthma

Intrinsic Asthma

Extrinsic Asthma

Mixed

Physiopathology

Obstruction of air flow

Increase in smooth muscle

Hypertrophy and cellular hyperplasia

Release of Acelticolin

Regulation of bronchial tone cells and proinflammatory cells

Airway Edema

Hypersecretion of mucus

Bronchial mucus plugging

Bronchoconstriction: Abnormal smooth muscle contraction of the airways, intrinsic abnormality in the airway myocytes

Release of fibrogenic growth factors

There’s a deposit of collagen and elastolysis.

Inflamattion airway by cellular remodeling

Decrease in air flow

Hyperreactivity of the respiratory tract

Narrowing of the airways in response to a known or unknown stimulus

Variable airflow limitation and intermittent symptoms

to both inflammation and repair of the airways

increased volume or contractility of smooth muscle cells

excessive airway contraction due to inflammatory changes

Response to sensory stimuli in sensory nerves sensitized by excessive inflammation

Bibliografy: Borja G. Cosio, Rodriguez J, Rosado, y Fiorentino F. Asthma: Epidemiology, Pathophysiology, and Risk Factors Clinical Respiratory Medicine, Chapter 38, 487-500. Río B. Navarro E. Castro M. Sierra J. Asthma. Departamento de Alergia, Hospital Infantil de México Federico Gómez, México, D. F., México. Vol 66.

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