Gram Negative Bacteria

Bacteria enter the body through :

urinary

ventilators

wounds

This can lead to pneumonia and such infections of the :

bloodstream

bones

joints

urinary tract

Can be difficult because of several
unique features of this bacteria

For example, the unique nature
of their cell wall makes them resistant
to several antibiotics

Appear pinkish or red

High Lypopolysaccharides

Thin peptidoglycan

Many infections occur through
cross contamination between people.

To reduce it, hand washing and having healthcare
workers wear gloves

Vaccines are not available for most healthcare-
associated caused by Gram negative bacteria.

New drugs to combat Gram negative bacteria
infections are needed.

Researchers are unraveling the molecular
mechanisms of drug resistance

to identify novel strategies to
combat these pathogens

NIAID-funded researchers are exploring these related to
Gram negative bacteria and the diseases they cause.

DNA translocation (across the
inner membrane)