NAR Database
how it is organize?
annually update or revised
year 2014: 185 articles published
58 new molecular biology database
recent update: 123 databases
devided to 8 section
1
nucleic acid sequence and structure
transcriptional regulation
2
protein sequence and structure
motive and domain
protein-protein interaction
3
metabolic and signaling pathway
enzymes
protein modification
4
viruses
bacteria
protozoa and fungi
5
human genome
comparative genomics
model organism
6
genomic variation
diseases and drug
7
plant database
8
molecular biology database
types of databse
protein domain database
InterPro
Protein Cluster
SBASE
protein sequence motif and active site
nucleotide sequence database
International Nucleotude Sequence Database Collaoration
nextProt
GenBank
metabolic and signaling pathway
enzyme and enzyme nomenclature
Binding DB
BRENDA
KEGG
PDB
Description
PDB : Protein database
KEGG : Database resource for understanding function and utilities of the biological system
BRENDA : Comprehensive enzymes information system
NextProt : New human protein-centric knowledge platform
Gen Bank : Sequence databease, annotated collection of all available nucleotide sequences and their protein translations
SBASE : Domain prediction system
Protein Cluster : Collection of related protein sequences consists of protein derieved from annotation of whole genomes, organelles and plasmids
Interpro : Integrated resource of protein
Binding DB : Binding database
Why it is useful?
Binding DB
measured binding affinities
have small collection of data for study supra molecular system
InterPro
usefull for functional analysis of protein sequence
predict present of domain and important sign
SBASE
facilitate the detection of functional homologies
GenBank
provide DNA sequence
Protein Cluster
provide collection of protein from complete genome of prokaryote, plasmid, viruses, organelles, protozoa, and plant
to know the protein cluster
NextProt
provide variety types of imformation on human protein
BRENDA
provide data collection of enzyme
PDB
for 3D prediction
KEGG
understanding high level function and utilities of biological system