There is a relationship between these two techniques because after a CAT or CT scan is done they may do a MRI to be sure of something
Biological Psychology

Biological Psychology

History of the Brain

History of the Brain

History of the brain

The brain has evolved over the past
few million years, it has chronologically
grew starting with:

1. Hind Brain

2. Limbic System

3. Neo Cortex

Ancient History

1700 Egyptian mummification practices

1700 Egyptian mummification practices

During this era they pulled out the brain through the nose; piece by piece they took it out with a hook

2500 BCE Trenpancition

2500 BCE Trenpancition

Created holes in the skull to remove the "idiot stone"

460 BCE Hippocrates

460 BCE Hippocrates

Father of modern medicine

Thought the brain told what us to do

387 BCE Plato

387 BCE Plato

335 BCE Aristotle

335 BCE Aristotle

Thought the brain was a hot and cool radiator for the body

Early Physician experiments

170 BCE

Roman physician Galen disected monkeys and pig brains, he believed that spirts throughout the body were housed in the brain

Roman physician Galen disected monkeys and pig brains, he believed that spirts throughout the body were housed in the brain

1500

Shortly after the ban on dissestion; Leonardo Di Vinci fashioned a wax cast of an ox brain after many disections of the human

Shortly after the ban on dissestion; Leonardo Di Vinci fashioned a wax cast of an ox brain after many disections of the human and animal brain

1664

Thomas Willis publishes the first brain atlas. This is considered the birth of neaurscience

Thomas Willis publishes the first brain atlas. This is considered the birth of neaurscience

1929

EEG was invented by Hans Berger

EEG was invented by Hans Berger

EEG is is a test used to find problems related to electrical activity of the brain. An EEG tracks and records brain wave patterns

1934

Egas Moniz carries out the first lobotomy operation. He also invented angiogrpahy: a medical imaging technique used to visual

Egas Moniz carries out the first lobotomy operation. He also invented angiogrpahy: a medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers.

Abnormalities and Traumas

Key Case Studies

1848: Phineas Gage

1848: Phineas Gage

He was an American railroad construction foreman remembered for his improbable survival of an accident in which a large iron rod was driven completely through his head, destroying much of his brain's left frontal lobe.

1953: Brenda Milner

1953: Brenda Milner

Neural Cells

Neural Cells

Structure of a neuron

Structure of a neuron

The soma is the body of the nerve cell

Information holder

The dendrites are the receivers that act as receptors for signals travelling from other neurons, carrying information toward the main body of the nerve cell.

Recievers

The axons are the senders that send out information to the other cells and is covered in a thick tissue called myelin sheath.

Sender

Synapses

Synapses is the release of one or more neurotransmitter.
The postsynaptic cell has receptors on he dendrites to receive the n

Synapses is the release of one or more neurotransmitter.
The postsynaptic cell has receptors on he dendrites to receive the neurotransmitter. The receptor never directly touches the other cell. There is a microscopic gap called the synaptic cleft, which the neurotransmitters travel across.

The more these neurons connect with eachother, the stronger the synaptic connection becomes. This creates strong neaural pathway

When one cells axon connects with another cells's dendrites they create a connection called a synapse or synaptic connection

Neurons communicate when two neurons connect with one another

After synapses the neurotransmitters clear the area by:

After synapses the neurotransmitters clear the area by:

1.Reuptake channels, the axon terminal of the cell reabsorbs many neurotransmitter molecules; the axon then recycles them to be used again

2.The enzymes present in the synaptic cleft destroy some neurotransmitter molecules

3.Still other molecules diffuse out of the cleft and are carried away as waste material by the cerebrospinal fluid

Neurotransmitters are chemicals in the brain that are generally either excitatory or inhibitory, which means they can either increase or decrease the likelihood of a neuron firing.

Neurotransmitters fall into 3 catagories

Amino Acids

Amino Acids

Glutamate: always carry excitatory messages

Glutamate: always carry excitatory messages

Glycine: always carry inhibitory messages

Glycine: always carry inhibitory messages

Aspartate: always carry excitatory messages

Aspartate: always carry excitatory messages

GABA: always carry inhibitory messages

GABA: always carry inhibitory messages

Amines

Epinephrine/Adrenaline- involved in stress response (fight-or-flight response).

Epinephrine/Adrenaline- involved in stress response (fight-or-flight response).

Norepinephrine/Noradrenalin- involved in arousal during fight-or-flight response.

Norepinephrine/Noradrenalin- involved in arousal during fight-or-flight response.

Dopamine - two major roles are to control conscious motor activity and enhance pleasurable feelings in the brain’s reward system (anticipated reward).

Serotonin- is a mood enhancer, but affects mood by calming rather than stimulating. Depression drugs inhibit the reuptake of serotonin thus increasing it’s effect.

Acetylcholine- can be inhibitory or excitatory (mostly excitatory) and is involved in muscle contraction (recall curare),  me

Acetylcholine- can be inhibitory or excitatory (mostly excitatory) and is involved in muscle contraction (recall curare), memory, and REM sleep.

Peptides

Peptides

Neuropeptides are lumped together loosely under a generic name Endorphins

Endorphins- creates a feeling of euphoria which helps as a pain killer.

Opioids are an addiction and depression

oxacillin and heroine

Psychoactive drugs interact with neurotransmitters meaning they affect mood, arousal or behaviour. They often allow us to predict how they'll affect us psychologically

opiates such as codeine function as agonists, which means they increase receptor site activiey. Reduce our emotional response to painful stimuli by binding wiht opiod receptoprs and mimicking endorphoins

Our brains have two types of cells. There are the glial cells and the neurons.

Glial Cells

Glial Cells

The glial cells are also known as neuroglia. Their function is to guide neurons towards making connections, promote neuronal health, and influence the functioning of the brain. The glial cells do not make their own connections.

Neurons

Neurons

The neurons are commonly found primarily in the brain and spinal cord (the central nervous system- CNS). Our bodies are capable of generating new neurons, but neurons do not regenerate in the same way as any other cells.

Neurons communicate through chemical and electrical signals. When the neauron becomes stimulated it recieves excitatory signals from another neuron. This results in a neauron being positively charged for a brief period of time known as action potential

Stem cells

Stem cells

Have the capacity to differentiate into a more specialzed cell

They can genetically engineered to provide therapy, providing the patient with replacement genes

Researchers can implant stem cells into the nervous system and induce them to grow and replace damaged cells

oriiginate in embryos

Structures and functions

Structures and functions

The Hind Brain

The Hind Brain

The brain stem consist of the medulla oblongata (lower), the pons (centre) and the midbrain (upper end)

The brain stem consist of the medulla oblongata (lower), the pons (centre) and the midbrain (upper end)

The pons (center area)- meaning bridge, acts as bridge from the medulla oblongata to the other brain regions, responsible for motor control and sensory analysis, and midbrain (upper end)- processes vision, hearing, and eye movement, the cerebellum- the role is to coordinate movement and balance

The medulla oblongata (the lower end)- where the spinal cord meets the brain stem, responsible for basic bodily functions such as heartbeat and respiration,

The midbrain processes vision, hearing and eye movement

The cerebellum role is coordinates movement and balance

The cerebellum role is coordinates movement and balance

There are 4 lobes:

There are 4 lobes:

1.Occipital- located at the lower central back of the brain. Primary function is to process visual information. The visual sy

1.Occipital- located at the lower central back of the brain. Primary function is to process visual information. The visual systems communicates with the other brain regions to determine if it has been stored and if the visual stimuli is meaningful

2.Temporal- main function is to process auditory stimuli. Responsible for hearing, language, and auditory memories

2.Temporal- main function is to process auditory stimuli. Responsible for hearing, language, and auditory memories

3.Parietal- Located at the top of the brain are flat. Responsible for spatial awareness and orientation

3.Parietal- Located at the top of the brain are flat. Responsible for spatial awareness and orientation

4.Frontal- Allows us to move parts of our body, think about the past, plan the future, focus attention, reflect, make decisio

4.Frontal- Allows us to move parts of our body, think about the past, plan the future, focus attention, reflect, make decision, achieve self-regulation, solve problems, and engage in conversation (Prefrontal Cortex: responsible for impulse control and executive functions. Impulse control)

Prefrontal Cortex is not fully developed until 25 years of age (on average). This part of the brain is newest evolutionarily speaking and responsible for impulse control and executive functions.

Limbic System

Hypothalamus

Hypothalamus

The pituitary gland controls the functions necessary for maintaining the normal state of the body homeostasis

Plays a role in regulating sex drive, sleep, agressive behaviour and pleasure.

hippocampus

hippocampus

Holds the memories from your immediate past and dispatches the memory to the cortex, where it is stores in longterm memory. Once a memory is fully encoded into long term memory, it would appear that the hippocampus is no longer needed for it to be retrieved

thalamus

thalamus

Two walnut sized structures joined by a bridge. The thalamus has been said to be the gateway to the cortex. This is the area of the brain that all sensory input goes to before it is sent off to the appropriate region of the brain

Amygdala

Amygdala

Two small almond, it is considered the brains alarm system

Plays a major role in the control of emotions. The amyglda forms unconscious memories based on emotional responses

Flight or flight response

Flight or flight response

An evolutionary mechanism that triggers our mind and body to respond to stressful and/or life threatening situations

Hemispherical Specialization

Hemispherical Specialization

Both Hemispheres are responsible for different things but
they work together due to the Corpus Callosum

Both Hemispheres are responsible for different things but
they work together due to the Corpus Callosum

Left Hemisphere

Responsible for the academic,
verbal and analytical things

Right Hemisphere

Responsible for the creative,
artistic and emotional things

Corpus Callosum: is a large bundle of nerve
fibers that connect the left and right
hemisphere and allows them to communicate

Corpus Callosum: is a large bundle of nerve
fibers that connect the left and right
hemisphere and allows them to communicate

The right hemisphere governs the
left side of the body and the left
hemisphere governs the right side
of the body

Brain Imaging

Brain Imaging

Four Neuroimaging techniques

PET

PET

Stands for Positron Emisson Tomography

Views the structure of the brain to
see which part if the brain is active
during specific task or events

During the PET scan

The part of the brain that is showing
the greatest activity shows up as red,
white and yellow

The part of the brain that shows
less activity is green, blue and puprle

Limitations of a PET Scan

PET scans require am ejection of a
radioactive tracer. It allows the
neruoscientist to view the flow of 
the blood, oxygen an

PET scans require am ejection of a
radioactive tracer. It allows the
neruoscientist to view the flow of
the blood, oxygen and glucose levels.

This is not recommened for children or adults in great doses

Delay in reading the functionsing
of the brain by 40 seconds

The PET scan does not directly
show the specific area in which
the activity is occurring

MRI

MRI

Stands for Magnetic resonance imaging

A more detailed 3D image of the
brain and gives a percise mapping
of the physical shape of the brain

Looks at the structure of the
brain, but gets a more details
pictures of the brain tissue

CAT/CT scans

CAT/CT scans

Useful for quick assesing of brain injuries

Looks at the structure only

Can also be any part of the body, not just the brain

A series of x-rays of the head are
taken from many different directions

Stands for Computerized technology

fMRI

fMRI

Stands for Functional Magnetic resonance imaging

Uses changes in blood flow to
generate images that show brain
activety and performance

Looks at the structure of the
brain and their functions

By:Camryn Wadsworth
& Komal Saleem