Categorieën: Alle - signaling - inflammation - immunity

door Ramzi Garvin 13 jaren geleden

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Eicosanoids

Eicosanoids are signaling molecules derived from 20-carbon essential fatty acids, primarily involved in immune and inflammatory responses. These molecules are not stored in cells but are synthesized as needed, and their production involves specific enzymes.

Eicosanoids

Eicosanoids

Eicosa (Greek) - Twenty

TWO ENZYMES

Leukotrienes
Chemotaxis of leukocytes
PROSTANOIDS
Promotion sleep, fever heat Inducing Pain inhibiting pain swelling

Inflammation

Asprin/NSAIDS
Down regulation of eicosanoid synthesis

20 Carbon Essential Fatty Acids

Dihomo-gammi-linolenic Acid
3 Double Bonds
Omega 6
Proinflammatory
4 Double Bonds
Omega 3
5 Double Bonds

Signaling Molecules

Not Stored in Cells

Immunity

Leukocyte Chemotaxis
Stimulation of Platelet aggregation
Inhibition of platelet aggregation