SNS Dominance- Biting down
Lack of hydration puts further burden on the kidney
Likely calcium deficiency
Lack of restorative sleep means microvilli can't heal properly which affects nutrient absorption
Low Bile Production likely
High Dietary Salt and regular consumption of Red Meat correlates with lower survival rates in CVD
Oxidative stress from low antioxidant activation and daily red meat increases BP
Dr prescribed Calcium tablets as low calcium is a regular pattern
Effect of microbiome diversity
Kidney strain
Lower survival if renal failure with high dietary salt
Antibiotics reduce microbiome diversity
Need Niacin for CVD protective effect
SNS Dominance increased by caffeine
High Systolic BP is often due to stress and diet imbalances
likely dehydration
Greater risk of CVD and hypertensioni ncreasing due to intracellular caclcium
Zinc required for HCL
NUTRIENTS NOT ABSORBING
SNS Dominance Heightened
95% serotonin (precursos for melatonin( is in gut
Less rate of survival expected if CVD event with high dietary salt
Dietary Antioxidants is already low. Activation is low
dehydrated
White spots could be calcium or Zinc deficiency

Jenny 64 y.o

Renal System

ACE Inhibitor Capoten and Thiazide Diuretic (which decreases blood volume) when taken together puts pressure on Renal System AND hyperactivation of Renin-Adosterone system which independently drives blood pressure up

Lymphatic system

Congested- likely congestion due to lack of hydration

Dietary Fluid

Water intake 4 cups

Caffeine

Medication

SUSTAINING FACTOR: Diuretics 30 years excrete the following minterals resulting in

Insufficient Zinc

Insufficient B vitamins

Required for resoration of all cells due to cofactor in Creb cycle. Niacin is protective against CVD events

Insufficient Magnesium

Magnesium deficiency results in sufficient activation of NA-K ATPase pump which bontrols and trasnports homeostatis of electroyltes and metabolses Vitamin D

Calcium supplement isn't a well absorbed form of calcium

EXCITORY FACTOR:Ace Inhibitor Capoten

Retain Potassium resulting in imbalanced Potassium: Sodium ratio which increases SNS dominance and results in kidney burden due to difficult renal vasodilation

Antibiotic Cephalexin

EXCITORY FACTOR: Cephalexin has been found to be increased AUC on intestinal level due to competitive methods of absorption with ACE inhibitors

Diet

Low Dietary Calcium

Low in Vitamin C and E- antioxidants

Regular consumption of Red Meat

High dietary salt at 368% of RDI

Lack of vegetables in diet resulting in lack of zinc and reduced fuel for healthy microbiome

Zinc levels insufficient

Zinc is required for Superoxide dismutase so this is downregulated resulting in higher levels of free radicals and oxidative stress

Lack of zinc for mucosal healing

Lack of Zinc required to make HCL

Difficulty absorbing B12, calcium, magnesium and iron due Zinc not present sufficiently as cofactor to synthesise transporter protein intrinsic factor req. for absorption of above minerals and also activation of Vitamin C

Lifestyle

Difficult sleep onset due to stress

Primary school teacher so indoors most of her life

Low Vitamin D

Nervous System

SNS dominance heightened by Caffeine and imbalance of Potassium: Sodium Ratio both independently linked to SNS dominance

Has a physical reaction to stress (urgent bowel motion in am)

Eye Twiches (Chvostek Sign)show Magnesium deficiency

Intractellular magnesium deficiency correlates positively with those who have hypertension because it causes greater intracellular calcium concentration resulting in calcium nail spots, vasoconstriction, vascular stiffness and endothelial dysfunction

Widow for eight years and son separated from his wife causing stress affecting her sleep onset problems (see serotonin production decreased due to microbiome diversity which is precursor to melatonin)

Cardio V. S

Cholesterol 4.4mol/L

Low plasma levels of both tryglycerides and cholesterol could mean chylomicrons could be collecting the cholesterol and transporting it to the liver

PREDISPOSING FACTOR: History of high Systolic Blood pressure for 30 years. Now 155/90 when usualy is 130/80

Risk of CVD or atherosclerosis due to high blood pressure, family history, downregulated superoxide dismutase increasing oxidative stress, low Vitamin A and high dietary salt (predisposes to arterial stiffening and higher blood pressure)

Tryglycerides 2.0

Low Vitality

Respiratory System

Hay Fever Every Spring. Uses Telfast

Family History

father possible oesteoperosis

Mother died of Stoke 74 years

Sister high cholesterol

Immune

Three upper respiratory infections in <12 weeks

History

HELP syndrome when pregnant including elevated liver enzymes

Differential Diagnosis

Atherosclerosis

SIBO due to high carbohydrate content in food and bowel dysbiosis after antibiotics

GIT

Stools likely to be loose due to urgency every am

Indicates inflammation

Fast gastric motility- See Link to SNS

Ageing parietal cells resulting in less HCL being produced impeding absorption of all nutrients and less intrinsic factor resulting in insufficient transport of nutrients intracellularly

Insufficient B12, calcium, magnesium and iron intracellularly and not enough activation of the antioxidant properies of ascorbic acid

Microbiome diversity decreased

PREDISPOSING FACTOR: IBS from 25y.o

Diarrhoeah every morning

Low pancreatic enzyme production resulting in impeded nutrient absorption for 40 years!

Hepatobilary System

Cephalexin 500mg and Capoten together
needing to be eliminated daily causing liver burden and reduced synthesis of bile required for nutrient absorption

Integumentary Sytem

Nails

White spots indicating likely zinc or calcium deficiency

Tongue scalloped shows hyperactivation of SNS