R & D, I TREATMENT FOR COVID-19

DRUGS SUGGESTION BY WHO

CHLOROQUINE and HYDROXYCHLOROQUINE

Trait

Trait

Trait

OBJECTIVE

TO TREAT THE PATIENT WITH SEVERE ACUTE RESPIRATORY SYMPTOMS.

CLINICAL TREATMENT BY USING IN VITRO POLYGONUM MINUS (KESUM)

DISCUSSION

THE BIOACTIVE COMPOUND EXTRACT LIKE FLAVANOID RICH IN ANTIOXIDANT ACTIVITY COULD BE USE TO IMPROVE OXIDATIVE STRESS

OXIDATIVE STRESS

LUNGS RESULTS WHEN THE ANTIOXIDANT ACTIVITY CAPACITY DEPLETED THROUGH EXTERNAL EXPOSURES (CAN SEE IN THE PATIENT THAT HAVING SHORTNESS OF BREATH OR DIFFICULTY BREATHING)

LUNGS CONDITION LIKE COPD AND ASTHMA

MOST OF THE PATIENT WILL HAVING TROUBLE WITH THEIR BREATHING CONDITION. SOME OF THE PATIENT NEED BREATHING AIDS LIKE VENTILATOR.

THE USE FLAVANOID IN THE CLINICAL TREATMENT DUE TO FREE RADICAL OF ANTIOXIDANT ACTIVITY COULD IMPROVES THE REDOX IMBALANCE DUE TO THIS VIRUS.

IDEA

ANTIOXIDANT TREATMENT, NATURAL ANTIOXIDANT FROM IN VITRO POLYGONUM MINUS (KESUM)

'KESUM' KNOWN AS MEDICINAL PLANT AMONG MALAYSIAN. SCIENTIFIC COMMUNITY BELIEVES THEIR CAPABILITY IN PHARMACOLOGICAL ACTION AND CAPABILITY TO TREAT VARIOUS DISEASE TOWARDS HUMAN.

THIS PLANT IS ONE OF THE MOST VEGETABLE USE AND MOSTLY FOUND IN SOUTHEAST ASIAN LIKE MALAYSIA.

'KESUM' PRESERVED BIOACTIVE COMPOUND OR SECONDARY METABOLITE LIKE FLAVANOID. THIS EXTRACT USE IN ANTIOXIDANT TREATMENT.

BASES ON THE STUDIES, PERCENTAGE OF BIOACTIVE COMPOUND IN IN VITRO PLANT IS HIGHER COMPARED TO NATURALLY GROWING IDEA. THE QUALITY AND QUANTITY OF 'KESUM' PRODUCTION FROM FIELD GROWN ARE OFTEN FLUCTUATING DUE TO ENVIRONMENTAL CONDITIONS.