Mechanisms of Signalling Network
Coincidence Defection
2 Pathway Converge upon coincidence defector which caused response.
Gating
Pprimary Cascade that produce response is influenced through gate by other pathway (Secondary Cascade)
Multiple Diversions
Signal from a protein take different pathway from node, with one pathway regulating the other.
Feedback Looping
Positive Feedback Looping
Signal from a protein activate 2nd protein which caused amplification & stabilization of signal
Negative Feedback Looping
Pathyway inhibited by product produced by transcription activator of same pathway. End point is dampening & limiting of signalling.
Double Negative Feedback Looping
When 2 protein inhibit each other