TREATMENT OF DM: ORAL HYPOglycaemics

Mais informações

pocket guide back packs mind map

por Matthew Smith

Total parenteral nutrition

por kassandra pineda

FORCES ACTING ON STRUCTURES and mechanism

por Sawban Chowdhury

CPI

por Shu Braque

TREATMENT OF DM: ORAL HYPOglycaemics

Alpha GluCOSidase Inhibitors

BIGuANIDES

Prandial Glucose Regulators (PGR)

SulphoNYLureas

S.Es

Secondary failure rate = 5-10% per yr

Hypoglycaemia

WEIGHT GAIN by increasing inulin secretion

Shud not give glibenclamide & chlorpropamide (=long-acting) 2 over 70s if live alone - fatal

Effective, well-tolerated & widely used

No lag period b4 response

High initial response

INCREASE insulin secretion

Examples:

ChlorPROpaMIDE

TolBUTAmide

GliPIzide

GliCLAzide

GliBENclaMIDE

ThiaZOlidiNEdiones (GlitaZONES)