Claremont Colleges Library: 7Cs Chemistry Curriculum: 2013-14

Harvey Mudd

Chemistry Club

Harvey Mudd

Creation, properties, and uses of materials structured on the nanometer length scale and their potential impact upon society.

Companion course to Chemistry 23 emphasizing chemistry fundamentals and problem-solving in a group setting.

Kinetics, equilibria, and acid/base chemistry.

Phase behavior, equations of state, intermolecular
forces, thermodynamics and electrochemistry.

Molecular and electronic structure, intermolecular forces, condensed phases, organic structure and properties and biopolymers.

Applications of thermodynamics, equilibria, electrochemistry, structure/property relationships, synthesis, spectroscopy and chemistry in the service of society.

Phase equilibria, thermodynamics and chemical kinetics.

Physical chemical measurements of molecular properties.

Applications of chemical equilibria in qualitative and quantitative analysis with emphasis on inorganic systems

A continuation of the chemistry of carbon compounds.

Chemical analysis.

Synthesis, characterization and analysis of organic compounds.

Two oral reports and a written thesis are required. 2 or 3 credit hours per semester. (2 credit hours equals a minimum of 6 hours of laboratory per week, 3 credit hours equals a
minimum of 10 hours of laboratory per week: additional library time is required.

Study of the metal carbon bond: synthesis, structure, bonding, reactivity and catalysis.

Advanced topics at the interface between chemistry and biology

Special readings in chemistry.

Discussions of contemporary research by students, faculty and visiting scientists.

Kinetics, equilibria, and acid/base chemistry.

Phase behavior, equations of state, intermolecular
forces, thermodynamics and electrochemistry.

Applications of thermodynamics, equilibria, electrochemistry, structure/property relationships, synthesis, spectroscopy and chemistry in the service of society.

A rotation through multiple research laboratories.

Introduction to quantum mechanics with application to atoms and molecules. Group theory. Survey of spectroscopic techniques.

A systematic study of the chemistry of carbon-containing
compounds, emphasizing synthesis, reaction mechanisms, and the relation of structure to observable physical and chemical properties.

Laboratory taken concurrently with Chemistry 56.

Systematic study of the preparation, properties, structures, analysis and reactions of inorganic compounds.

Synthesis and characterization of inorganic compounds.

Instrumental methods of analysis.

Special topics in analytical chemistry including instrumental analysis, electrochemistry, and chemometrics.

Two oral reports and a written thesis are required. 2 or 3 credit hours per semester. (2 credit hours equals a minimum of 6 hours of laboratory per week, 3 credit hours equals a
minimum of 10 hours of laboratory per week: additional library time is required.

Relation of molecular structure and energy flow to reactions in living systems.

Experiments in biochemistry.

Special readings in chemistry.

Discussions of contemporary research by students, faculty and visiting scientists.

Elements of chemical engineering for chemists. Organization and goals of industrial research. Readings, case studies and seminar discussions.

Lasers in chemistry. Introduction to the principles of the operation of lasers.

Biophysical chemistry. Physical chemistry applied to answer questions involving the conformation, shape, structure, dynamics and interactions of biological macromolecules and
complexes.

Electronic structure theory. An examination of modern methods for approximating the solution to the electronic Schroedinger Equation and its application to chemical systems.

Advanced group theory. A survey of topics selected from: space groups and crystals; permutation groups and molecular isomerization; rotation groups and angular momenta; double groups and magnetism; groups of non-rigid molecules; the symmetry of graphs.

Surface science. Structure and chemical properties of surfaces as detailed by a range of analytical techniques.

Organic synthesis. Critical analysis of strategies for the preparation of medicinal natural products. Prerequisite: one year of organic chemistry.

Pericyclic reactions. The application of molecular orbital theory and symmetry considerations to certain types of organic reactions in order to gain insight on the mechanisms and stereochemistry of the processes.

Integrative experience course that studies the molecular biology of HIV infection, the biochemistry of antiviral interventions, and the causes and impact of the global HIV-AIDS pandemic, including the interrelationships among HIV-AIDS, prejudice, race, and stigma. Students will complete a community service project in partnership with a local AIDS organization.

Materials science of energy conversion and storage.

An introduction to basic thermodynamic, kinetic and structural principles; ionic equilibria; and the physical and chemical properties of the more common chemical elements and their compounds. Laboratory work is coordinated with the lecture and emphasizes quantitative analytical and instrumental techniques and molecular modeling. Interactive computing is an integral part of the second semester. High-school chemistry recommended.

Accelerated introductory course for well-prepared students. Ionic equilibrium, atomic structure, molecular bonding and structure, chemical thermodynamics and chemical kinetics. Laboratory work emphasizes quantitative analytical and instrumental techniques and molecular modeling. Interactive computing is an integral part of the course. Prerequisite: two or more years of high school chemistry and a passing score on the placement examination.

Organic Chemistry with Lab. A study of organic compounds, including synthesis and reaction mechanisms. Laboratory includes both synthesis and qualitative organic analysis.

Biological molecules considered in terms of their structure and roles in the dynamic processes by which energy and information are received, interconverted and transmitted in order to maintain life. Laboratory emphasizes techniques and instrumentation used to study the nature of biochemical molecules and processes.

Quantum mechanics with applications to chemical bonding and molecular spectroscopy, molecular modeling, introduction to statistical mechanics and kinetic gas theory.

Study of modern instrumental methods of analysis with an emphasis on optical and X-ray spectroscopy, mass spectrometry, and high performance gas and liquid chromatography. Efficient experimental designs are used to make multivariate investigations by students working in formal groups.

Introduction to the theory and practice of computational chemistry, including numerical methods, molecular mechanics/dynamics, and electronic structure calculations. Model chemistries will be discussed and compared in lecture along with their range of applicability. Laboratory exercises emphasize learning how to apply a variety of commercial and free software to chemical problems in biochemistry and materials chemistry. Lecture with 3-4 laboratory exercises.

Basis for a clearer understanding of the structures of organic compounds, the mechanisms of organic reactions and how they fuse together at the molecular and cellular level. Examples drawn from drug and pesticide design, as well as environmental toxicology. Interactive computing using specific software is an integral part of the course.

An interdisciplinary course provides a basic understanding of the key underlying mechanistic principles of drug interactions at the molecular and cellular level. Topics include physicochemical principles of drug design and action, receptor-effectors theories, receptor characterization, DNA interactions, drug distribution and metabolism, as well as pro-drug chemistry. Lecture/Computational Lab.

The thesis requirement can be satisfied in one of two ways, beginning in the second semester of the junior year or in the first semester of the senior year: 1) The student writes a critical review of a topic of current interest and significance, or 2) the student writes a thesis describing experimental research conducted in the laboratory of a faculty member. Students writing a critical review select a topic and conduct library research; students writing an experimental thesis continue with laboratory work normally initiated through summer research or an independent study. In both cases, students submit an abstract of their thesis for departmental review. Students writing the thesis present it, or parts of it, orally at a departmental seminar.

Syllabus reflects workload of a standard course in the department or program. Examinations or papers equivalent to a standard course. Regular interaction with the faculty supervisor. Weekly meetings are the norm. Available for full- or half-course credit.

A substantial and significant piece of original research or creative product produced. Prerequisite course work required. Available for full- or half-course credit.

Lab notebook, research summary or other product appropriate to the discipline is required. Half-course credit only.

An introduction to basic thermodynamic, kinetic and structural principles; ionic equilibria; and the physical and chemical properties of the more common chemical elements and their compounds. Laboratory work is coordinated with the lecture and emphasizes quantitative analytical and instrumental techniques and molecular modeling. Interactive computing is an integral part of the second semester. High-school chemistry recommended.

The pleasure and the nourishment we derive from food and drink are both based on the chemical composition of our diets. We will focus in this class first on the chemical composition of wine and all the grape-growing and winemaking decisions which impact that composition. We will also discuss sensory analysis of wine and food. The food part of the class will then look at the chemical changes that take place during cooking, and how those changes influence our perception of and the nutritional value of food. This class is a non-majors class but additional reading will be offered for chemistry majors.

An examination of environmental systems such as the atmosphere and the oceans from a molecular perspective. The course will critically examine chemical sources of environmental pollution and the means for remediation of these problems.

A study of organic compounds, including synthesis and reaction mechanisms. Laboratory includes both synthesis and qualitative organic analysis.

Biological molecules considered in terms of their structure and roles in the dynamic processes by which energy and information are received, interconverted and transmitted in order to maintain life. Laboratory emphasizes techniques and instrumentation used to study the nature of biochemical molecules and processes.

The application of physical chemistry to biochemistry and molecular biology. A study of chemical thermodynamics, chemical kinetics, and spectroscopy related to the determination of molecular structure and molecular interactions.

Study of chemical thermodynamics, chemical kinetics, statistical thermodynamics and chemical dynamics.

Advanced physical chemistry topics chosen from the areas of statistical thermodynamics, group theory, chemical kinetics, molecular modeling and solid state chemistry. Laboratory emphasis on modern instrumental methods, including molecular spectroscopy, powder X-ray diffraction, nuclear magnetic resonance, chemical kinetics and gas-phase adsorption.

Examines fundamental concepts in nuclear magnetic resonance with a focus on spectroscopic techniques used for organic structure elucidation and conformational analysis. Hands-on experience with data collection and analysis.

An examination of biochemical catalysis with an emphasis on enzyme mechanisms and techniques used in their elucidation. Current primary literature is studied to gain an understanding of what is known and perhaps more importantly, not known, about catalysis in chemistry and enzymology.

This course, which builds on foundations in both chemistry and molecular biology, will address the following questions: (1) What is chemical biology and (2) What can chemical biology do to advance science and human health? Students will consider varying definitions of "chemical biology" and explore examples of each of these views. Topics may include small molecule screens to decipher biological networks, genetic control with small molecules, directed evolution, self-replication, and approaches towards next-generation antimicrobials.

This course is concerned with the self-assembly of functional materials at the nano-scale. The first half of the course covers the fundamentals of surface chemistry, monolayer formation and the chemistry of colloidal systems; the second half highlights nano-fabrication methods used to assemble complex nanomaterials for applications in biophotonics, chemical sensing, optics and electronics.

Chemical and physical principles will be used to describe the complex system of the Earth's atmosphere. Atmospheric structure, design of simple models, and atmospheric transport will be covered followed by selected topics concerning geochemical cycles, the greenhouse effect, aerosols, stratospheric ozone, smog and acid rain.

The thesis requirement can be satisfied in one of two ways, beginning in the second semester of the junior year or in the first semester of the senior year: 1) The student writes a critical review of a topic of current interest and significance, or 2) the student writes a thesis describing experimental research conducted in the laboratory of a faculty member. Students writing a critical review select a topic and conduct library research; students writing an experimental thesis continue with laboratory work normally initiated through summer research or an independent study. In both cases, students submit an abstract of their thesis for departmental review. Students writing the thesis present it, or parts of it, orally at a departmental seminar.

Syllabus reflects workload of a standard course in the department or program. Examinations or papers equivalent to a standard course. Regular interaction with the faculty supervisor. Weekly meetings are the norm. Available for full- or half-course credit.

A substantial and significant piece of original research or creative product produced. Prerequisite course work required. Available for full- or half-course credit.

Lab notebook, research summary or other product appropriate to the discipline is required. Half-course credit only.

Inorganic chemistry is a lecture based class that includes descriptive chemistry of the elements (s, p and d blocks) as well as a variety of advanced topics such as electronic structures, symmetry, molecular orbital theory, acid/base chemistry, bonding and structure of solids, organometallics and catalysis.

A lecture course emphasizing the design and evaluation of synthetic routes to organic molecules.

An in-depth view of protein structure and enzyme catalysis and how protein structure and properties are linked to biological function. Topics include chemical properties of polypeptides, protein biosynthesis, post-translational modifications, protein-protein interactions, structure and function relationships, evolutionary and genetic origins of proteins and enzyme kinetics and mechanisms. This course makes use of bioinformatics tools available over the Internet.

Keck Science

This course is an introduction to the basic concepts of medicinal chemistry and the methods of biochemical analysis, such as: drug discovery, development, and commercialization; a discussion of chemical bonding and the organic functional groups found in drug molecules; and an examination of the physiochemical properties related to drug action (e.g., acid-base properties, equilibria, and stereochemistry). Laboratory Fee $30. Offered occasionally.

Spring 2014

An introduction to basic thermodynamic, kinetic and structural principles; ionic equilibria; and the physical and chemical properties of the more common chemical elements and their compounds. Laboratory work is coordinated with the lecture and emphasizes quantitative analytical and instrumental techniques and molecular modeling. Interactive computing is an integral part of the second semester. High-school chemistry recommended.

The pleasure and the nourishment we derive from food and drink are both based on the chemical composition of our diets. We will focus in this class first on the chemical composition of wine and all the grape-growing and winemaking decisions which impact that composition. We will also discuss sensory analysis of wine and food. The food part of the class will then look at the chemical changes that take place during cooking, and how those changes influence our perception of and the nutritional value of food. This class is a non-majors class but additional reading will be offered for chemistry majors.

Kinetics, equilibria, and acid/base chemistry.

Applications of thermodynamics, equilibria, electrochemistry, structure/property relationships, synthesis, spectroscopy and chemistry in the service of society.

A rotation through multiple research laboratories.

Introduction to quantum mechanics with application to atoms and molecules. Group theory. Survey of spectroscopic techniques.

A systematic study of the chemistry of carbon-containing
compounds, emphasizing synthesis, reaction mechanisms, and the relation of structure to observable physical and chemical properties.

Laboratory taken concurrently with Chemistry 56.

This course is an introduction to the basic concepts of medicinal chemistry and the methods of biochemical analysis, such as: drug discovery, development, and commercialization; a discussion of chemical bonding and the organic functional groups found in drug molecules; and an examination of the physiochemical properties related to drug action (e.g., acid-base properties, equilibria, and stereochemistry). Laboratory Fee $30. Offered occasionally.

Systematic study of the preparation, properties, structures, analysis and reactions of inorganic compounds.

An examination of environmental systems such as the atmosphere and the oceans from a molecular perspective. The course will critically examine chemical sources of environmental pollution and the means for remediation of these problems.

Synthesis and characterization of inorganic compounds.

A study of organic compounds, including synthesis and reaction mechanisms. Laboratory includes both synthesis and qualitative organic analysis.

Instrumental methods of analysis.

Special topics in analytical chemistry including instrumental analysis, electrochemistry, and chemometrics.

Biological molecules considered in terms of their structure and roles in the dynamic processes by which energy and information are received, interconverted and transmitted in order to maintain life. Laboratory emphasizes techniques and instrumentation used to study the nature of biochemical molecules and processes.

Two oral reports and a written thesis are required. 2 or 3 credit hours per semester. (2 credit hours equals a minimum of 6 hours of laboratory per week, 3 credit hours equals a
minimum of 10 hours of laboratory per week: additional library time is required.

The application of physical chemistry to biochemistry and molecular biology. A study of chemical thermodynamics, chemical kinetics, and spectroscopy related to the determination of molecular structure and molecular interactions.

Study of chemical thermodynamics, chemical kinetics, statistical thermodynamics and chemical dynamics.

Advanced physical chemistry topics chosen from the areas of statistical thermodynamics, group theory, chemical kinetics, molecular modeling and solid state chemistry. Laboratory emphasis on modern instrumental methods, including molecular spectroscopy, powder X-ray diffraction, nuclear magnetic resonance, chemical kinetics and gas-phase adsorption.

Electronic structure theory. An examination of modern methods for approximating the solution to the electronic Schroedinger Equation and its application to chemical systems.

Examines fundamental concepts in nuclear magnetic resonance with a focus on spectroscopic techniques used for organic structure elucidation and conformational analysis. Hands-on experience with data collection and analysis.

Pericyclic reactions. The application of molecular orbital theory and symmetry considerations to certain types of organic reactions in order to gain insight on the mechanisms and stereochemistry of the processes.

An examination of biochemical catalysis with an emphasis on enzyme mechanisms and techniques used in their elucidation. Current primary literature is studied to gain an understanding of what is known and perhaps more importantly, not known, about catalysis in chemistry and enzymology.

Relation of molecular structure and energy flow to reactions in living systems.

Experiments in biochemistry.

Integrative experience course that studies the molecular biology of HIV infection, the biochemistry of antiviral interventions, and the causes and impact of the global HIV-AIDS pandemic, including the interrelationships among HIV-AIDS, prejudice, race, and stigma. Students will complete a community service project in partnership with a local AIDS organization.

Harvey Mudd

Goals for Chemistry Education at HMC

For all Harvey Mudd students to understand the fundamental principles of chemistry and to have the background necessary to understand the impact of chemistry on our society.

Students will demonstrate a basic knowledge of chemistry in the area of

structure

dynamics

energetics

Students will demonstrate an understanding of society’s demands upon chemistry as well as the advances in quality of life made possible by chemical science.

For all Harvey Mudd students to understand how fundamental chemical principles can be applied to the solution of real problems in a variety of technical fields.

Students will demonstrate sufficient background and depth in chemistry to be able to successfully complete any of the majors offered at Harvey Mudd College.

Students will demonstrate that they have appreciated the contributions of chemistry to at least one problem facing society.

For all Harvey Mudd students to understand how chemists successfully study and interpret chemical and physical phenomena through experimental investigations using high-quality modern instrumentation.

Students will demonstrate that they can keep an adequate record of experimental investigations.

Students will demonstrate that they can execute an experiment to measure a chemical property using typical instrumentation.

Students will demonstrate that they can interpret results of experimental measurements via the application chemical theory.

Goals for the Chemistry Major at HMC

For all Harvey Mudd chemistry graduates to have a broad and intense education in chemistry, approved by the American Chemical Society, so that they may succeed in any professional career track they choose.

Senior chemistry majors will be able to demonstrate a mastery of factual knowledge comprehensively across the five principal areas of chemistry (organic, inorganic, physical, analytical, and biochemical), and be able analyze and solve problems, understand relationships, and interpret scientific facts and data.

Students completing the chemistry major will meet the certification requirements as set forth by the American Chemical Society Committee on Professional Training

Students completing the joint major in chemistry and biology will have the option of earning certified degrees in biochemistry with the addition of one to two courses.

Chemistry graduates will be successful in gaining entrance into high quality graduate schools in chemistry and allied field, admission to professional schools, and securing quality careers in the chemical sciences and other fields.

For all Harvey Mudd chemistry graduates to have a quality research experience for so that they may understand the ways in which new scientific knowledge is created.

Students will demonstrate that they can independently find and use information pertinent to their research efforts.

Students will demonstrate an understanding of the relationship of their project to the current literature.

Students will demonstrate an understanding of the broader impacts of their work on society.

Students will demonstrate that they can design and execute an experiment to test a hypothesis or answer a specific question.

Students will demonstrate that they can analyze experimental results, draw appropriate conclusions, and suggest next steps.

Students will demonstrate that they can effectively communicate the findings of their work in oral, visual, and written form.

Students will master and apply an experimental or theoretical technique at a level beyond that presented in the core chemistry curriculum.

For all Harvey Mudd chemistry graduates to develop the ability to communicate scientific ideas clearly and effectively.

Students will demonstrate that they can produce a thesis describing an open question in the field of chemistry, its context, a method of addressing that question through experimental work, the results of the study, and pertinent conclusions.

Students will demonstrate that they can frame an open question in the field of chemistry in the course of a short oral presentation, utilizing audio-visual aids of high quality.

Students will demonstrate that they can, through research conducted in the major courses and through Senior Thesis, report on their contributions to an open question in the field chemistry through an oral presentation of sufficient length and depth, utilizing audio-visual aids of high quality.

Students will demonstrate that they can frame an approach to solving an open question in the field of chemistry and communicate it to an educated layperson in the space of two printed pages.

Be able to apply knowledge of chemistry, physics and math to solve chemical problems

Possess a breadth of knowledge in analytical, physical, organic, analytical, inorganic and bio-chemistry

Be able to identify, formulate and solve complex problems

Have a mastery of techniques and skills, used by chemists

Chemistry major learning goals

Harvey Mudd

Surface and Interfacial Properties of Organic Thin Films

Theoretical studies of ground and excited states of molecules

Development of new regioselective reactions for synthesis

Interactions between proteins and nucleic acids; RNA interference and gene therapy approaches for treating HIV-AIDS

Characterization of light-absorbing compounds in atmospheric aerosol

Amino acid-derived ligands for the synthesis of chiral transition metal complexes and novel ligands for the synthesis of heterobimetallic complexes

Spectroscopic studies of surfactant assemblies, host-guest systems, and drug-delivery vehicles

Synthesis and spectroscopic characterization of bio-inspired transition metal complexes

Thermodynamics of liquid crystals

Self-assembling molecular systems, energy and electron transfer, and solar energy conversion.

Biomimetic cyclizations and natural product synthesis

Keck Science

Kersey Black

Physical organic chemistry, with an emphasis on computational approaches to understanding organic reaction mechanisms

Anthony Fucaloro

David E. Hansen

The design and synthesis of self-assembling organic nanostructures

Mary Hatcher-Skeers

Dynamics of protein-DNA interactions
Solid-state and Solution NMR spectroscopy
Effects of DNA Methylation

Aaron Leconte

Biomolecular evolution. Protein engineering. DNA polymerases.

Thomas Poon

Photochemistry, synthetic methodology, natural products, zeolite chemistry, and pedogogy

Kathleen Purvis-Roberts

Urban Air Pollution, Environmental Impacts of Nuclear Testing in Semipalatinsk, Kazakhstan

Babak Sanii

Materials that self-heal
Protein folding with model systems
Low-cost and 3D printed scientific equipment

Anna G. Wenzel

Asymmetric Catalysis, Organometallic Chemistry, and Organic Synthesis

Nancy S.B. Williams

Physical Organometallic Chemistry, Ligand Design and Effects on Fundamental Organic Transformations

Andrew W. Zanella

Transition metal complexes: nitrile hydration; proton exchange on complexed nitriles; electron transfer reactions.

Chemistry; Random-Walk Calculations; Thermodynamics; Statistical Mechanics; Statistical Mechanics and Scientific translation English/Spanish

My research is in the area of molecular theory of thermodynamics, with emphasis on problems in the theory of random-walk calculations, phase transitions and stochastic processes. We also use molecular mechanics and dynamics to study biological processes.

Chemistry; Molecular Ion Spectroscopy; Free-Jet Expansion Spectroscopy; Laser Spectroscopy, Laboratory Study of Atmospheric Relevant Reactions

1) Gas-phase spectroscopy of molecular ions and transition metal compounds via electron impact and laser excitation of free-jet expansions. Recent projects have included the discovery and analysis of electronic spectra of dimethylzinc cation, deuterated dimethylzinc cation and dimethylcadmium cation.

2) Atmospheric Chemical Reactions, particularly peroxy radical reactions (Collaboration with Stan Sander and Mitchio Okumura)

Malkiat Johal

His research activities focus on using self-assembly and ionic adsorption processes to fabricate nano-materials for optical and biochemical applications. Undergraduate research students are heavily involved in both the construction of and the detailed characterization of ultra-thin assemblies. These functional materials include bioactive surfaces (immobilized proteins) within polyelectrolyte multilayers, asymmetrically orientated surfactant multilayers, and self-assembled polyelectrolytes with desirable photoluminescent, photovoltaic and NLO-active properties. Professor Johal’s laboratory also explores fundamental phenomena such as ion-pair complexation, adsorption, surface wettability, and intermolecular non-covalent interactions that lead to highly ordered structures. His laboratory is also exploring the use of functionalized stacked waveguides and piezoelectric quartz crystal resonators as platforms for chemical and biological detection, catalysis, and the nano-fabrication of photovoltaic and organic LED materials. Research students in his laboratory use a variety of surface analysis tools including Dual Polarization Interferometry, Quartz-Crystal Microbalance with Dissipation Monitoring, Surface Tensiometry, Spectroscopy (e.g. ATR-FTIR), X-Ray Reflectivity, Multi-Wavelength Ellipsometry, and Contact Angle analysis.

Chemical Biology; Molecular Biology; small RNAs

An organism's genome encodes all of the biochemical instructions needed to produce a living cell. The transcriptional programs of a cell, however, are dynamic, changing as the cell develops, grows and responds to alterations in the environment. The control of gene expression is not well understood but all living cells require it. Understanding these networks is fundamental for understanding human health and combating disease. Because intrinsic properties of RNA make them ideal for rapid switches that modulate gene expression in response to changes in environment, my lab hypothesizes that novel, functional RNA motifs represent ubiquitous elements in numerous gene networks that allow cells to develop, grow, adapt and survive. The broad goals of my research are to identify and understand, at a molecular level, the many ways by which RNA contributes to normal cell function, and to apply this gathered knowledge to the development of novel tools and potential therapeutics.

I use a model organism to study the control of gene expression by non-canonical RNA: the prokaryotic Vibrio cholerae. The following are two on-going projects in the lab that address my interests and goals: (1) Investigate the mechanisms by which non-canonical RNAs mediate bacterial survival; (2) Engineer biosensors to monitor pathogenesis regulation in V. cholerae.

Chemistry; Organic Chemistry; Nuclear Magnetic Resonance Spectroscopy

As an organic chemist, I am interested in developing new methods for determining the solution conformation of molecules. Students in my laboratory synthesize target compounds designed to mimic motifs found in nature, they then employ the technique of Nuclear Magnetic Resonance to probe the solution conformation of the designed systems.

Nucleation and Phase Transitions; Liberal Arts Colleges; Science Education; Liquids

As President, I am interested in liberal arts colleges and the future of education in the twenty-first century. I have particular expertise in science education and active learning approaches, and in the international dimensions of education. My work in environmental chemistry has focussed on atmospheric chemistry and the science of global climate change. My research interests in chemistry involve thermodynamics and statistical mechanics, including the study of phase transitions and nucleation, crystal growth, and amphiphile fluids and self-organization.

Organic chemistry; Bio-organic chemistry; Medicinal chemistry

Chemistry; Biochemistry; Structural Biology; Bacterial Biolfilms

Prof. Sazinsky's research activities employ X-ray crystallography and biochemical techniques as primary tools to answer important questions about the structure and function of proteins. The major research themes are to identify the determinants of metalloenzyme activity and tuning, re-engineer proteins for altered functions and/or expanded catalytic capabilities, and to provide a basis for understanding the biochemical processes in pathogenic bacteria. Undergraduate research students are heavily involved in the structural and biochemical characterization of specific protein targets.

Chemistry; Analytical Chemistry; Electron Microscopy; Microhotplate Arrays, Environmental Monitoring

As an analytical chemist, I am interested in providing students with practical experience by applying chemistry to develop new materials. Students in my research lab will use specialized equipment to probe the relationship between a material's properties and the chemistry used to prepare it. This insight will enable them to design application-specific chemical sensors and make subtantive contributions on a current project with researchers at the Jet Propulsion Laboratory, who are developing an electronic nose.

Harvey Mudd

Major

Joint Major B.S. in Chemistry & Biology

Options

B.S. in Chemistry with an emphasis in Applied Chemistry

Chem 166 and either 103 with 109 or 114 with 112. Three courses selected from Eng 82, 106, 133, or 136.

B.S. in Chemistry with an emphasis in Computational Chemistry

Chem 52, 112, and 114. Three courses selected from Chem 105, 161, 168D, KSD Chem 134, CS 60, Eng 176, Math 164, or Phys 116.

B.S. in Chemistry with an emphasis in Education

Chem 103, 109, 197-198 as 3 credit hours of student teaching, and CGU Educ 170B. One course selected from Chem 52, 105 with 111, 114 with 112, or 189 with 184.

B.S. in Chemistry with an emphasis in Environmental Chemistry

Chem 103, 109, 112, and 114. Six credit hours selected from Eng 138, KSD Chem 139, PO Chem 106 or 188.

B.S. in Chemistry with an emphasis in Geochemistry

Chem 103, 109, 112, and 114. Two courses selected from PO Geo 120, 121, or 127 with laboratory.

B.S. in Chemistry with an emphasis in Materials

Chem 52, 112, and 114. Three courses selected from Chem 105, 193A, Eng 106, or Phys 162.

Requirements

Phase equilibria, thermodynamics and chemical kinetics.

Introduction to quantum mechanics with application to atoms and molecules. Group theory. Survey of spectroscopic techniques.

Physical chemical measurements of molecular properties.

A systematic study of the chemistry of carbon-containing
compounds, emphasizing synthesis, reaction mechanisms, and the relation of structure to observable physical and chemical properties.

Laboratory taken concurrently with Chemistry 56.

Applications of chemical equilibria in qualitative and quantitative analysis with emphasis on inorganic systems

Systematic study of the preparation, properties, structures, analysis and reactions of inorganic compounds.

A continuation of the chemistry of carbon compounds.

Chemical analysis.

Synthesis and characterization of inorganic compounds.

Synthesis, characterization and analysis of organic compounds.

Instrumental methods of analysis.

Special topics in analytical chemistry including instrumental analysis, electrochemistry, and chemometrics.

4-6 hours of 151 or 152

Two oral reports and a written thesis are required. 2 or 3 credit hours per semester. (2 credit hours equals a minimum of 6 hours of laboratory per week, 3 credit hours equals a
minimum of 10 hours of laboratory per week: additional library time is required.

Relation of molecular structure and energy flow to reactions in living systems.

4 Semesters of 199

Discussions of contemporary research by students, faculty and visiting scientists.

Chemistry

Chemistry 1A,B or 51

Chemistry 110A

Chemistry 110B

Chemistry 158B

Chemistry 161

Math 30

Math 31

PHYS 51A, 51B or equivelent

Chemistry 158A

Chemistry 162

Chemistry 191A

Chemistry 191B

Math 32 or 107

two elective course credits chosen from chemistry courses numbered above 100

Biochemistry

Chemistry 115

Chemistry 1A,B or 51

Chemistry 110A

Chemistry 110B

Chemistry 158B

Chemistry 161

Math 30

Math 31

PHYS 51A, 51B or equivelent

Chemistry 158A

Chemistry 191A

Chemistry 191B

Math 32

Math 107

two elective course credits chosen from chemistry courses numbered above 100 (Chemistry 180 recommended)

Geochemistry

Chemistry 1A,B or 51

Chemistry 110A

Chemistry 110B

Chemistry 158B

Chemistry 161

Math 30

Math 31

PHYS 51A, 51B or equivelent

Chemical Engineering

Chemistry 1A,B or 51

Chemistry 110A

Chemistry 110B

Chemistry 158B

Chemistry 161

Math 30

Math 31

PHYS 51A, 51B or equivelent

For the Chemistry minor, students must complete a minimum of six Chemistry courses, including CHEM 1,B (or 51); 110A,B; 158A or 158B; and one upper-division elective

Keck Science

Chemistry 14L-15L. Basic Principles of Chemistry, or Chemistry 29L. Accelerated General Chemistry, or both semesters of the AISS course

Chemistry 116L-117L. Organic Chemistry

Chemistry 121-122. Principles of Physical Chemistry

Physics 33L-34L. Principles of Physics, or Physics 30L-31L. General Physics, with permission of adviser, or both semesters of the AISS course

Chemistry 126L-127L. Advanced Laboratory in Chemistry

Chemistry 128. Inorganic Chemistry

Chemistry 177. Biochemistry

Electives: one advanced elective (or two halves) in chemistry, biochemistry, molecular biology, or interdisciplinary electives involving chemical concepts of techniques, chosen in consultation with the chemistry faculty

Senior Thesis in Chemistry: chemistry majors must complete a one- or two-semester thesis in Chemistry - students must do a two-semester thesis (Chem 188L-Chem 190L or Chem 189L-Chem 190L) to complete the ACS accredited major in Chemistry.

NOTES: Mathematics 31, Calculus II is co-required of Chemistry 121, and Mathematics 32, Calculus III is co-required for Chemistry 122 and Biology 43L, Introductory Biology is co-required for Chemistry 177. Additional electives in chemistry, mathematics, physics and computer science are strongly recommended for all chemistry majors.

A dual major in chemistry requires seven upper-division chemistry courses, in addition to senior thesis. This reduces the load of a regular chemistry major by two courses. The seven courses must include: Organic Chemistry 116L and 117L, Physical Chemistry 121 and 122, at least one semester of Advanced Laboratory (either 126L or 127L), and either Inorganic Chemistry 128 or Biochemistry 177. The remaining elective can consist of either a single upper-division course or two halves. All lower-division courses and prerequisites in other disciplines (math, physics) must still be met. Students doing a dual major in chemistry are not eligible for the ACS accredited major.

Sean Stone - Chemistry Liaison Librarian

Cynthia Cohen - STEM Librarian

Chemistry Research Guide

Prior Library Instruction

2011-12

A study of organic compounds, including synthesis and reaction mechanisms. Laboratory includes both synthesis and qualitative organic analysis.

2012-13

The thesis requirement can be satisfied in one of two ways, beginning in the second semester of the junior year or in the first semester of the senior year: 1) The student writes a critical review of a topic of current interest and significance, or 2) the student writes a thesis describing experimental research conducted in the laboratory of a faculty member. Students writing a critical review select a topic and conduct library research; students writing an experimental thesis continue with laboratory work normally initiated through summer research or an independent study. In both cases, students submit an abstract of their thesis for departmental review. Students writing the thesis present it, or parts of it, orally at a departmental seminar.

2014

Future IL Instruction/Intervention Targets & Outcomes

Physical chemical measurements of molecular properties.

IL Learning Outcomes

Inquiry

Evaluation

Attribution

Discussions of contemporary research by students, faculty and visiting scientists.

IL Learning Outcomes

Evaluation

Communication

Insight

An introduction to basic thermodynamic, kinetic and structural principles; ionic equilibria; and the physical and chemical properties of the more common chemical elements and their compounds. Laboratory work is coordinated with the lecture and emphasizes quantitative analytical and instrumental techniques and molecular modeling. Interactive computing is an integral part of the second semester. High-school chemistry recommended.

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Accelerated introductory course for well-prepared students. Ionic equilibrium, atomic structure, molecular bonding and structure, chemical thermodynamics and chemical kinetics. Laboratory work emphasizes quantitative analytical and instrumental techniques and molecular modeling. Interactive computing is an integral part of the course. Prerequisite: two or more years of high school chemistry and a passing score on the placement examination.

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A study of organic compounds, including synthesis and reaction mechanisms. Laboratory includes both synthesis and qualitative organic analysis.

IL Learning Outcomes

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The thesis requirement can be satisfied in one of two ways, beginning in the second semester of the junior year or in the first semester of the senior year: 1) The student writes a critical review of a topic of current interest and significance, or 2) the student writes a thesis describing experimental research conducted in the laboratory of a faculty member. Students writing a critical review select a topic and conduct library research; students writing an experimental thesis continue with laboratory work normally initiated through summer research or an independent study. In both cases, students submit an abstract of their thesis for departmental review. Students writing the thesis present it, or parts of it, orally at a departmental seminar.

IL Learning Outcomes

Evaluation

Communication

Insight

IL Learning Outcomes

Inquiry

Evaluation

Attribution

IL Learning Outcomes

Evaluation

Communication

Attribution

IL Learning Outcomes

Evaluation

Communication

Insight