Cardiovascular Drugs

Cardiac Glycocides

Digoxin/Lanoxin

+ Inotropic

- chronotropic

- dromotropic

Antidote Digibind

Dobutamine/Dobutrex

+ Beta 1 agonist

+inotropic, CHF

Monitor BP and Heart

Emergency Drug

Antidysrhythmics

I  Fast sodium channel blockers A,B,C

A. Procainamide/Pronestyl & quinidine

decreases conduction velocity & automaticity

increases time for repolarization

Lessens likelihood of ectopic beats

B. Lidocain/Xylocain

Slows conduction

Prolongs repolarization

raises ventricular firing threshold

C. No Prototype

Suppress PVC

Slows conduction

II  Beta Blockers (lol)

Acebutolol (Sectral), Metoprolol (Lopressor), Propranolol (Inderal) (non-selective)

Slow heart rate

Block effect Catecholamines

Dysrhythmias (especially Ventricular)

Angina

High BP

Blocks Beta-1 (antagonist)

III  Prolong Repolarization

Amiodarone/Cordarone  (one)

Emergency treatment of V-fib and V arrhythmias

increases refractory period

prolongs action potential

IV Calcium Channel Blockers

Diltiazem/Cardizem, Verapamil/Calan

Decrease excitability and contractility of myocardium

increase refractory period of AV node

slows conduction

Atrial Fib and Flutter

Diuretics

Furosemide/Lasix

High Ceiling Diruetic

fast action

Can increase renal blood flow 40%

HTN, Edema, renal disease

Na, H2O excretion at loop

Hydrochlorothiazide/Diuril

For HTN and Peripheral Edema

Na, Cl, H2O excretion @ distal tubial

2 Hours

Triamterene/Dyrenium

Potassium Sparing

Collecting Tubial

Weak

Spironolactone/Aldactone (ATI)

Potassium Sparing

Collecting tubial

Weak

Mannitol/Osmitrol

EMERGENCY DRUG

Lower fluid levels FAST

Osmotic

filter needle, keep warm r\t crystals

ICP

Nitroglycerine/Nitrostat

For Angina

Dilates Blood vessels

Reduces preload

Decreases workload

Viagra + Nitro = VERY BAD DAY

Cardiac and BP monitoring + Call MD if Systolic < 90

Beta Blockers

Lower HR

Lower contractibility

Nonselective not for COPD or asthma

Diltiazem/Cardizem

Calcium Channel Blocker

lowers HR in A-fib or flutter

Decreases Angina from coronary artery spasm

- Chronotropic

- Inotropic

- Dromotropic