Jenny 64 y.o
Integumentary Sytem
Tongue scalloped shows hyperactivation of SNS
Nails
White spots indicating likely zinc or calcium deficiency
Hepatobilary System
Cephalexin 500mg and Capoten together
needing to be eliminated daily causing liver burden and reduced synthesis of bile required for nutrient absorption
GIT
Microbiome diversity decreased
PREDISPOSING FACTOR: IBS from 25y.o
Low pancreatic enzyme production resulting in impeded nutrient absorption for 40 years!
Diarrhoeah every morning
Ageing parietal cells resulting in less HCL being produced impeding absorption of all nutrients and less intrinsic factor resulting in insufficient transport of nutrients intracellularly
Insufficient B12, calcium, magnesium and iron intracellularly and not enough activation of the antioxidant properies of ascorbic acid
Stools likely to be loose due to urgency every am
Indicates inflammation
Fast gastric motility- See Link to SNS
Differential Diagnosis
SIBO due to high carbohydrate content in food and bowel dysbiosis after antibiotics
Atherosclerosis
History
HELP syndrome when pregnant including elevated liver enzymes
Immune
Three upper respiratory infections in <12 weeks
Family History
Sister high cholesterol
Mother died of Stoke 74 years
father possible oesteoperosis
Respiratory System
Hay Fever Every Spring. Uses Telfast
Low Vitality
Cardio V. S
Tryglycerides 2.0
Risk of CVD or atherosclerosis due to high blood pressure, family history, downregulated superoxide dismutase increasing oxidative stress, low Vitamin A and high dietary salt (predisposes to arterial stiffening and higher blood pressure)
PREDISPOSING FACTOR: History of high Systolic Blood pressure for 30 years. Now 155/90 when usualy is 130/80
Cholesterol 4.4mol/L
Low plasma levels of both tryglycerides and cholesterol could mean chylomicrons could be collecting the cholesterol and transporting it to the liver
Nervous System
Widow for eight years and son separated from his wife causing stress affecting her sleep onset problems (see serotonin production decreased due to microbiome diversity which is precursor to melatonin)
Eye Twiches (Chvostek Sign)show Magnesium deficiency
Intractellular magnesium deficiency correlates positively with those who have hypertension because it causes greater intracellular calcium concentration resulting in calcium nail spots, vasoconstriction, vascular stiffness and endothelial dysfunction
Has a physical reaction to stress (urgent bowel motion in am)
SNS dominance heightened by Caffeine and imbalance of Potassium: Sodium Ratio both independently linked to SNS dominance
Lifestyle
Bold
Primary school teacher so indoors most of her life
Low Vitamin D
Difficult sleep onset due to stress
Diet
Lack of vegetables in diet resulting in lack of zinc and reduced fuel for healthy microbiome
Zinc levels insufficient
Difficulty absorbing B12, calcium, magnesium and iron due Zinc not present sufficiently as cofactor to synthesise transporter protein intrinsic factor req. for absorption of above minerals and also activation of Vitamin C
Lack of Zinc required to make HCL
Lack of zinc for mucosal healing
Zinc is required for Superoxide dismutase so this is downregulated resulting in higher levels of free radicals and oxidative stress
High dietary salt at 368% of RDI
Regular consumption of Red Meat
Low in Vitamin C and E- antioxidants
Low Dietary Calcium
Medication
Antibiotic Cephalexin
EXCITORY FACTOR: Cephalexin has been found to be increased AUC on intestinal level due to competitive methods of absorption with ACE inhibitors
EXCITORY FACTOR:Ace Inhibitor Capoten
Retain Potassium resulting in imbalanced Potassium: Sodium ratio which increases SNS dominance and results in kidney burden due to difficult renal vasodilation
Calcium supplement isn't a well absorbed form of calcium
SUSTAINING FACTOR: Diuretics 30 years excrete the following minterals resulting in
Insufficient Magnesium
Magnesium deficiency results in sufficient activation of NA-K ATPase pump which bontrols and trasnports homeostatis of electroyltes and metabolses Vitamin D
Insufficient B vitamins
Required for resoration of all cells due to cofactor in Creb cycle. Niacin is protective against CVD events
Insufficient Zinc
Dietary Fluid
Caffeine
Water intake 4 cups
Lymphatic system
Congested- likely congestion due to lack of hydration
Renal System
ACE Inhibitor Capoten and Thiazide Diuretic (which decreases blood volume) when taken together puts pressure on Renal System AND hyperactivation of Renin-Adosterone system which independently drives blood pressure up
