ALZHEIMER´S DISEASE

DEFINITION

A progressive neurological condition that causes brain shrinkage, cell death, memory loss, and cognitive decline. It affects concentration, decision-making, and mood, impairing daily functioning.

CAUSES

Likely due to a mix of genetic, lifestyle, and environmental factors that disrupt brain proteins, leading to neuron damage.

SYMPTOMS

- MCI: Minor memory and thinking changes.
- Mild Dementia: Impaired memory, problem-solving, and behavior.
- Moderate Dementia: Significant memory loss, confusion, and daily assistance needed.
- Severe Dementia: Loss of communication, physical decline, and full-time care needed.

HISTORY

Initially classified as general dementia before the 1970s. The term "Alzheimer's" emerged in 1984, with a 1990s focus on brain damage caused by plaques and tangles.

TREATMENT

No cure. The medication increases acetylcholine levels, which helps nerve cells communicate and improves memory and thinking.

Rivastigmine

Donepezil

PROGNOSIS

Life expectancy post-diagnosis ranges from 3-11 years, with a highly variable progression rate.