ALZHEIMER´S DISEASE
DEFINITION
A progressive neurological condition that causes brain shrinkage, cell death, memory loss, and cognitive decline. It affects concentration, decision-making, and mood, impairing daily functioning.
CAUSES
Likely due to a mix of genetic, lifestyle, and environmental factors that disrupt brain proteins, leading to neuron damage.
SYMPTOMS
- MCI: Minor memory and thinking changes.
- Mild Dementia: Impaired memory, problem-solving, and behavior.
- Moderate Dementia: Significant memory loss, confusion, and daily assistance needed.
- Severe Dementia: Loss of communication, physical decline, and full-time care needed.
HISTORY
Initially classified as general dementia before the 1970s. The term "Alzheimer's" emerged in 1984, with a 1990s focus on brain damage caused by plaques and tangles.
TREATMENT
No cure. The medication increases acetylcholine levels, which helps nerve cells communicate and improves memory and thinking.
Rivastigmine
Donepezil
PROGNOSIS
Life expectancy post-diagnosis ranges from 3-11 years, with a highly variable progression rate.