DATABASE Group member: Nurul Aisyah Afifah Liyana Noor Atiqah Norfariza Ronalizah
Importants of Databases
Uniprot
important to find out the sequences of our protein
analyse the functional information of the protein
KEGG
to find out the detail of biological activities of our protein
study the whole function our protein
Pfam
contain the family tree our protein
can study the structure and alignment of protein
CAZy
determine in detailed the activity and metabolism of our protein towards carbohydrate
Gene3D
to study the 3D structure of protein and each sequences of the structure
Criteria that need to be fulfilled to be inserted into NAR database
discuss the topic of interest
emerging or specialized subject areas
single cell gene regulation studies
nuclear architecture and functional consequences
gene targeting and Genome Engineering
genome studies using massive parallel(Deep) sequencing
molecur machines and complex molecular assemblages
single molecule studies of macromolecular function
synthetic Biology and Chemistry
Computational biology
Description of a new algorithm that represents a substantial improvement over current methodology and has direct biological relevance
Describe the use of existing computational method to generate significant novel biological information
Gene regulation,chromatin and epigenetics
genome integrity,repair and replication
genomics
nucleic acid enzymes
RNA
structure assembly,mechanism of action and regulation of ribosomes,snRNPs and other stable ribonucleoprotein particles
Structure,biogenesis,cellular roles and regulation of non-coding RNAs
new information about the structure and biochemistry of nucleic acid binding proteins or enzymes that function in RNA metabolism
Structural biology
Molecular biology
must update regularly
Can be access without interface or paywall
New and Updated NAR Database
Nucleic Acid Sequence and Structure, Transcriptional Regulation
microRNA Databases
miRBase
miRNEST
mirTarBase
PolymiRTS
starBASE
NONCODE Database
Various type of non-coding RNA
Transcription Factor Binding Sites (TFBSs)
JASPAR
YEASTRACT
Protein Sequences and Structure, Motifs and Domains, Protein-protein Interactions
annual update
uniprot and KEGG
popular database
Pfam
eggNOG
ELM
2 new database
HRAP
Repeats database
structural database
NDB
RNA bricks
protein structure database
RDBe
visualization
analysis of the electron microscopy derived structure
NCBI (MMDB)
calculated using VAST +
protein-protein interaction
Negatome database
Protein SCOP Database
SCOPe
SCOP Hierarcy
SCOP2
Metabolics and Signalling Pathways, Enzymes, Protein Modification
Metabolics Pathway Databases
MetaCyc
Reactome
Small Molecule Pathway
Catalytic Site Atlas
Structure-Function Linkage Database (SFLD)
Carbohydrate-Active enzyme Database (CAZy)
Merops
EKPD
MultiTaskDB
Viruses, Bacteria, Protozoa and Fungi
Human Microbiome Project
Genome Annotation
Human Pathogen
IMG
PATRIC
SEED
Free-living Microorganism
CynoBase
PortEco
Rhizobase
SubtiWiki
Microbial Diversity in Natural Enviroment
JGI'S IMG/M
EBI metagenomics resources
Sequence of Microbial Genome
Ribosomal Database Project (RDP)
the SILVA/LTP project
BacDive
Taxonomic
MetaRef
Human Genome, Model Organisms, Comparative Genomics
Human Genome
dbGaP
database of genotyping result
related to clinically relevant phenotype
Consensus CDS Project
collaborative effort to identify a core set of human protein region
Model Organism Databases
Saccharomyce Genome Database (SGD)
WormBase
FlyBase
Mouse Genome Database (MGD)
Mouse Gene Expression Database
Mouse Phenome Database
Vertebrate Genome Annotation (VEGA)
International Mouse Phenotyping Consortium (IMPC)
Genomic Variation, Diseases and Drugs
NCBI's ClinVar
database documenting clinically relevant sequences variant
NHGRI GWAS Catalog
a curated resources of SNP-Treat Association
Sanger institute's DECIPHER
database of pathogenic single nucleotide variant, indels and copy-number variant
Database of Genomic Variant (DGV)
canSAR
DriverDB
FINDbase
HbVar
Lynx
NECTAR
Progenetix
Plant Databases
Others Molecular Biology Databases
Organization of Databases in NAR
Nucleotide Sequence Databases
International Nucleotide Sequence Database Collaboration
BioSample
GenBank
Coding and Non-coding DNA
Dfam
Patome
Gene Structure, introns and exon, Splice side
GeneTack
ECgene
Transcriptional Regulator Sites and Transcription Factors
JASPAR
3D-Footprint
RNA sequence Databases
BPS
MeRNA
snOPY
Protein Sequence Databases
General Sequence Databases
Patome
UniProt
Protein Properties
REFOLD
Cybase
Structure Databases
BARD
Small Molecule
SuperDrug
DrugBank
Protein Structure
DBAli
Genome3D
Gene3D
Genomic Databases ( Non-Vertebrate)
MGD-mouse genomic database
The Gene Indices
Viral Genome Databases
HFV Database
ViralZone
Metabolic and Signalling Pathway
ChemProt
Protein-protein Interaction
IBIS
GeneNet
Enzyme and Enzyme nomeclature
BRENDA
ORENZA
Human and Other Veterbrate Genomes
Model Organisms, Comparative Genomics
AgBase
GeneSpeed
Human Genome Database, Maps Viewers
GeneAnnot
HOWDY
Human Genes and Diseases
CancerResource
Protein Mutant Database
Cancer Gene Databases
MethyCancer
CancerGene
Microarray Data and Other Gene Expression Databases
Gene Expression Barcode
HemBase
Sebida
Proteomics Resourses
GELBANK
MOPED
MAPU
Molecular Biology Databases
Network Portal
PubMed
CellFinder
Drug and Drug Design
PharmGed
SuperDrug
Molecular Probe and Primer
PrimerBank
VirOligo
Organelle Databases
Organelle Genome
GOBASE
Metochondrial Genes and Protein
MITOMAP
HMPD
Plant Databases
Chloroplast Genome Database
General Plant Databases
GeneFarm
PGDD
Immunological Databases
Epitome
MUJEN MOUSE DATABASE
Cell Biology
NCBI BookShelf
CloneDB
Different Type of Databases
UniProt
Database of protein sequences and functional information
UniProtKB
UniRef
UniParc
KEGG
Database resources for understanding high level function and utilities of the biological system
KEGG GENOME
KEGG GENES
KEGG DISEASES
KEGG DRUG
Pfam
Database of protein families that include annotation and multiple sequences aligments generated using hidden Markov models
CAZy
Database of Carbohydrate-Active enzymes which contains classification and associated information about enzymes involved in the systhesis, metabolism and transport of carbohydrates.
CAZypedia
Gene3D
To find out the protein domain, sequences features and 3D structures
CATH
Genome3D
InterPro