ubiquitin signal for degra
activate/inactivate
segment is removed activating it
different exon/introns combinations
C bases in promoter
chromatin remodeling complex or acetlylation
AA chain leaves, ribosomal detaches from mRNA
adds AA from p site
stop codon
another tRNA binds A site
Methionine tRNA forms complex in p site of small subunit
adds amino acid corresponding complementary to anticodon
eukaryote
activators/repressors
form intitation complex, help RNA poly bind

Molecular Genetics

Transcription

Intiation

elongation

termination

modifications: pre mRNA>mature mRNA

Rna splicing, group of ribonucleoproteins(snRPS) called splicesome bring exons close cleave out introns

poly a tail, G cap

Translation

tRna

Rna string, binds to itself
forming clover shape

Aminoacylation, by aminoacyl tRNA synthetase enzyme

Ribosome

intiation

G cap bind to complex, scan for AUG, large subunit is added

Elongation

Peptidly transferase

Ribsome shifts 1 codon, a >p, p>e

Termination

protein release factor binds

prokaryote

binds to itself in hairpin loop

proteins bind to mRNA

eukaryote

nuclear protein bind to termination site(string of adenines)

RNA polymerase bind Promoter

Builds 5' to 3', reads 3' to 5', template strand is bottom

open double helix

Regulation

chromatin accessability

Sepearting tighly wrapped histones

Methylation: Inhibits tanscrip

epigentics

post transcrip

Alternate splicing

masking proteins: inactivate

Translastional

rate of mRNA degradation:
Poly a tail, proteins, hormones

Inactive protein

chem modificationa

Rate of protein degradtion

Transcription factors bind

general factors