Schizophrenia and Cannabis
Summary of Relationship
Premorbid behaviour
Common brain pathology
2x
Cannabinoid System
What
Sativ and indica
Cannabinoid
CBD and CBN - Sedative
THC - Psychotropic effects
Effects
Reduced anxiety
Euphoria
Problematic
Social
Mental
Unpredictable Psychosis
1 in 10
Withdrawal
Anxiety, Insomnia
Epidemiology
4% WW
Increasing
Complications
Schizophrenia
Drug induced psychosis
Short lived
75% Psychiatric illness 12/12
50% in 3y
Early use
4x
Neural pruning
Onset Schizophrenia
Genetics
Inc. Cannabinoid R.
Susceptible
Inc. Endogenous cannabinoids
Inc. Cannabinoid R