MACRONUTRIENTS
CARBOHYDRATES
Very important source of quick energy.can be quite large, but relatively simple biochemical moleculesServe as important structural components.Composed of Carbon, Hydrogen and Oxygen arranged in a variety of configurations
Monosaccharides
Simplest type of carbContains a single sugarGenerally have a ratio of 1 carbon : 2 hydrogen : 1 oxygenFunction: building blocks for more complex carbs and energy sourceAll monosaccharides can occur in a linear form, however when formed in water, monosaccharides with five or more carbon atoms fold back on themselves to form a ringThis ring forms occurs through a reaction between 2 functional groups in the same monosaccharide
ex: Glucose
Plants produce Glucose during photosynthesis, and it provides energy for many functions in plants and animalsperhaps the most widely used monosaccharideWhen the polar carbonyl group interacts with a polar hydroxyl group, this forms a ring structure. (They have strong intermolecular forces of attraction like dipole-dipole and hydrogen bonding among each other, and nearby molecules)When glucose forms a ring structure it can form two different isomers, alpha-glucose or beta-glucose. The different arrangement of the -OH group on glucose can give chemicals different properties. ex: humans can digest starches composed of alpha-glucose, however cellulose, which is made from beta-glucose, is indigestible for humans.Glucose, fructose and galactose are isomers of each other (have the same chemical formula as one another, but a different arrangement of atoms).
ex: Fructose
Glucose, fructose and galactose are isomers of each other (have the same chemical formula as one another, but a different arrangement of atoms)When the polar carbonyl group interacts with a polar hydroxyl group, this forms a ring structure. (They have strong intermolecular forces of attraction like dipole-dipole and hydrogen bonding among each other, and nearby molecules)
ex: ribose + deoxyribose
Disaccharaides
Consist of 2 monosaccharides that are joined together by a dehydration synthesis reaction.Bonds that link monosaccharides into larger carbon hydrates are called glycosidic bonds.A glycosidic bond forms between a-glucose and fructose monosaccharide, resulting in the disaccharide sucrose.Disaccharides contain the same functional groups that make monosaccharides hydrophilic, therefore they are easily dissolved in water.Function: energy source
ex: Maltose
Forms through the linkage of two a-glucose molecules, with oxygen as a bridge between the 1-carbon of one glucose unit and the 4-carbon of the second glucose unit.
Oligosaccharides
Short chain of monosaccharidesLess than 20 monosaccharides linked together.A disaccharide can be referred to as an oligosaccharide.
ex: Maltotriose
Contains 3 glucose molecules.
Polysaccharides
A polysaccharide molecule is a chain of monosaccharides with many subunits joined by glycosidic linkages.A polysaccharide is a macromolecule, which is a very large molecule assembled by the covalent linkage of smaller subunit molecules.Dehydration synthesis reactions that assemble polysaccharides are examples of polymerization.Polymerization is the process where subunits called monomers, link together in a long chain to form a larger molecule called a polymer. ex: DNA is a type of polymerPolysaccharides may be very long linear, unbranched molecules, or they may contain branches in which side chains of sugar units attach to a main chain.Polysaccharides are very polar, and therefore very hydrophilicThey attract water, but cannot dissolveFunctions of polysaccharides include energy storage, structural support and cell-to-cell communication.
Homopolysaccharides
Contains only a single type of monosaccharide. ex: only glucose molecules linked together.Can be unbranched or branched.
ex: Starch
Storage for monosaccharides in plants. It is the main carbohydrate in the human diet.Only made up of glucose.Unbranched = AmyloseBranched = Amylopectin
ex: Glycogen
Unbranched = AmyloseBranched = AmylopectinBranch points occur more frequently in Glycogen
ex: Cellulose
Main component of plant cell wallsCellulose molecules are long and straight and have very large numbers of polar OH groups.These features allow many cellulose molecules to assemble side by side and form hundreds of thousands of hydrogen bonds.These hydrogen bonds give cellulose fibres their great strength.
Heteropolysaccharides
Contains 2 or more types of different monosaccharides. ex: a long chain of fructose and glucose molecules.can be unbranched or branched.
PROTEINS
Muscle tissue in meat and fish is rich in protein, as well as beans, seeds, milk products, eggs and nuts.Proteins are made up of amino acids.The shape of proteins is also determined by the type of intermolecular forces of attraction between monomers.Proteins carry out nearly all membrane processes. They act as receptors and help transport molecules in and out of the cell.
Amino Acids
There are 20 different types of amino acids. Humans can make 11 of these amino acids, and the remaining 9, which are called essential amino acids, must come from our diet.Amino acids with polar or ionic functional groups make stronger intermolecular forces of attraction. They can be described as hydrophilic.Amino acids with non-polar functional groups make weaker intermolecular forces of attraction. They can be described as hydrophobicAmino acids all contain an amino group, a carboxyl group, a Hydrogen atom, and an "R" groupThe "R" group represents one of 20 different side chains, one for each amino acid.When amino acids combine, they are always bonded to connect the carboxyl group of one amino acid, to the amino group of the next.The connection of amino acids is called a peptide bond.
Primary Structure
The primary structure of a protein in the unique linear sequence of its amino acids in each polypeptide chain.Amino acids link up into a linear chain of amino acids linked together by peptide bonds (called a polypeptide)
Secondary structure
This primary structure then folds or coils in different ways to make secondary structures.Structure begins to bend and fold because of intermolecular forces of attraction between amino acids in the same polypeptide chain.They are small, folded shapes within a protein, caused by hydrogen bonding.
Tertiary structure
Finally it bends into a whole 3D shape due to a range of bonding interactions among the amino acid R groups.These intermolecular reactions include ionic bonds, hydrogen bonds, hydrophobic interactions, and disulphide bridges. This tertiary structure is a strong bond that holds two parts of the polypeptide strand together, stabilizing its shape.The tertiary structure is critical to the functions of proteins, especially enzymes.
Quaternary structure
Proteins can work together in their quaternary structure.Some proteins will only function when they combine with other protein subunits.It is a combination of more than one protein with folded tertiary structures.The same bonds and forces that fold single polypeptide chains into tertiary structures also hold the multiple polypeptide chains together.
Proteins Used in the Body
Signaling
Signalling proteins allow cells to communicate with each other,Signals, receptors, and relay proteins work together to get information from the outside of a cell to the inside.Signalling proteins are messenger proteins such as hormones.
ex: hormones
Chemical Signaling in the Body
Hydrophobic chemical signals
Hydrophobic chemical signals include modified amino acids, like thyroxine, and the lipids molecules called steroids.Hydrophobic interactions are the attractive interaction between non-polar molecules, especially in a solvent like water.
Hydrophilic chemical signals
Hydrophilic chemical signals include proteins and modified amino acids.
Amphipathic
An amphipathic molecule, is a molecule with both hydrophobic and hydrophilic parts. It contains both polar and non-polar functional groups.
Enzymes
Enzymes build and break down molecules. They are critical for growth, digestion, and many other cell processes.Without enzymes, chemical reactions would happen too slowly to sustain life
Lactase
Helps infants digest lactose, a sugar in their mom's milk.
DNA polymerase
Builds DNA molecules. It reads the old DNA strand and inserts the correct nucleotides into the new strand.
Structural
Structural proteins provide framework supportStructural proteins strengthen cells, tissues, organs and more.Nature can build materials that are very strong.
ex: Hair, tendons, ligaments, collagen
Carrier (transport)
Carrier proteins help to transport materials throughout the cell
ex: hemoglobin
Hemoglobin molecule is composed of four polypeptides, each consisting of more than 140 amino acids.
LIPIDS
Lipids are hydrophobic molecules (non-polar) and do not dissolve in water.Lipids are composed mostly of hydrogen, carbon and lesser amounts of oxygen.Functions of lipids include: -storage and source of energy -hormonal roles -insulation -protection -structural components -lubrication
Triglycerides
Insoluble in water (hydrophobic)Fats are solid at room temperatureOils are liquid at room temperatureThey are made up of 1 glycerol and 3 fatty acids
Fatty acids
Fatty acids contain a carboxyl group linked to a hydrocarbon chain.Function: cellular functions and energy storage.As fatty acids move about, they take an organized shape called a micelleThe fatty acids have hydrophilic and hydrophobic portions, which interact in different ways with the surrounding environment (creating this micelle shape)
Saturated Fat
Saturated fats are not good for you.They are made up of fatty acid chains linked to glycerol, with single bonds.Function: energy storage and insulationex: fats obtained from animals such as butter and lard.Saturated fats are solids because their chains are long and straight and can be packed closely together to form a solid at room temp.
Unsaturated Fat
Unsaturated fats are good for you.They are made up of fatty acid chains linked to glycerol, with 1 or more double bonds.Function: energy storage and insulationIn their chemical structure, both hydrogens are on the same side of the double bond, and both carbons are on the same side (CIS).ex: fats derived from plants, such as olive oil.They become less fluid as the length of their fatty acid chain increases. Those with shorter chains remain liquid.
Trans Fat
Trans fats are bad for you.In their chemical structure, hydrogens and carbons are on either side of the double bond.Trans fats are made by partially hydrogenating unsaturated fats.
Phospholipids
Phospholipids make a structure called the phospholipid bilayer, an important structural feature of cells.Phospholipids are comprised of two fatty acid chains and one phosphate group linked to glycerol.The hydrophilic end of a phospholipid faces outward toward water, and the hydrophobic fatty acid tails face inward toward each other.The membrane, "fluid mosaic" includes:Phospholipids: They make up most of the cell membrane and are the building blocks for the cell membrane to exist.Cholesterol: they are in between cell membranes. They are scattered randomly throughout the cell membrane and help create fluid of the membraneProtein: carry out nearly all membrane processes.
Steroids
Steroids are a group of lipids with structures that are made up of four fused carbon rings.Small differences in the side groups that attach to these rings, distinguish one steroid from another.Function: hormonal signalling, cell response to the environment, and growth
Cholesterol
Cholesterol is an important component of the plasma membrane that surrounds animal cells.Cholesterol is essential for animal cell membranes and converts into a number of compounds, such as Vit D.
Testosterone
Waxes
Waxes are large lipid molecules that are made of long fatty acid chains linked to alcohols or carbon rings.Waxes are hydrophobic, extremely non-polar, and soft solids at varying temperatures.Their functions are water resistance and protection.ex: wax coating on fruits, leaves and stems
NUCLEIC ACIDS
Out of all the macronutrients, the monomer of Nucleic Acids, a nucleotide, is the most complex.Polymer forms of Nucleic Acids make 3D structures as a result of intermolecular forces of attraction.Nucleic Acids have predictable rules for which nitrogenous bases are attracted to each other.
Nucleotides
A nucleotide in a monomer of nucleic acidsEach nucleotide is a monomer composed of 3 parts:One or more phosphate functional groupsA five-carbon sugar (ribose OR deoxyribose)A nitrogenous baseNucleotides are connected between their phosphate group and a hydroxyl group on the 5-carbon sugar to make a phosphdiester bond DNA and RNA are both polymers, with their monomers made up of nucleotides.
RNA
Ribose is used to make polymers of RNARibose is also used to make monomers like ATP, and dinucleotides that perform other functions for the cellSingle stranded or double stranded (made up of two polymers)Single stranded Nucleic Acids can fold up on themselves to make functional shapesTransfers genetic informationCan be used to synthesize proteinCan be found outside of the nucleusEach nucleotide in RNA consists ofFive-carbon sugar, Ribosea phosphate groupone of four nitrogen bases: A, C, G, URNA is the hereditary molecule in some viruses.
ATP
ATP is made of the purine adenine.Smaller package of energy that comes in the form of a nucleic acid called ATPATP is the main energy carrying molecule. The energy is stored in the phosphodiester bond between the middle and end phosphate groups.In autotrophs, like plants, sunlight energy is captured first as ATPMost of this energy is used by the autotroph in its daily biological processes.As matter is passed to heterotrophs, only about 5-20% of the original energy is passed on.In consumers, enzymes convert the energy consumed into ATP.
mRNA
Messenger RNA is the copy of instructions form DNA.It is usually linear, but sometimes folds up on itself.
rRNA
Ribosomal RNA is a part of the ribosome and is important in reading the code in mRNA in order to combine the correct amino acids to make a protein.Inside the ribosome, it is partially linear, and partially folded.
tRNA
Transfer RNA is a molecule that moves amino acids to the ribosome and in doing so, binds to the mRNA. tRNA is folded up in three helical sections.
DNA
Deoxyribose is used to make polymers of DNASingle or double stranded. Double stranded forms an alpha-helixWhen two strands come together, they always line up and connect with one strand inverted compared to the other (antiparallel)Stores genetic informationServes at the library of the cellLocated in the nucleusNitrogen bases: A, G, C, TDNA is the hereditary molecule in eukaryotes, prokaryotes, some viruses, mitochondria and chloroplasts.
Nitrogenous Bases
There are five common nitrogenous bases:guanine (G)adenine (A)cytosine (C)thymine (T)uracil (U)C-G : Make a very strong bond. They are attached with 3 hydrogen bonds.A-T : They are attached with 2 hydrogen bonds.With hydrophobic interactions, the bases want to attach to one another. Bases are in the middle of DNA (hydrophobic), the phosphates (sugar backbone) like to be attracted to water (hydrophilic)
Purines
2 ringed structureConsist of A, G
Guanine
Adenine
Pyrimidines
1 ring structureConsist of C, T, and U
Thymine
Uracil
Cytosine