viruses

Accelular Agents

viruses

virion

bacteriophages

eukaryotic viruses

viroids

satellites

prions

Viral multiplication

mechanism

Attachment (Adsorption)

viral entry and uncoating

synthesis stages

assembly

virion release

Cultivation and Enumeration of viruses

requires inoculation of appropriate living host

hosts for

bacterial and Archaea

agar cultures

animal viruses

tissue cultures

cytopathic effects

embryonated eggs

plant viruses

plant tissue cultures

plant protoplast cultures

viroids and satellites

viroids

infectious agents of closed, circular ssRNAs

do not encode gene

requires host cell

satellites

infectious nucleic acids (DNA / RNA)

encode one or more gene products

Prions

Proteinaceous Infectious Particle

Neural loss

virion structure

structure

size: 10-400nm

contain nucleocapsid (DNA and RNA)

Envelopes

capsid

helical

icosahedral

complex symmetry

viral envelopes

flexible, membranous layer

animal virus envelope

viral envelope protein

virion enzymes

virion genome

DNA

RNA

Segmented

circular

Types of viral infection

infection in bacteria and Archeae

lysogenic conversion

Archeae Viruses

infection in eukaryotic cells

cytopathic effects

transformation to malignant cell

viruses and cancer

tumor

neoplasia

anaplasia

metastasis