Drugs in body

Circulatory System

- bloodstream transport of drugs

- rapid distribution throughout the body

- initial drug exposure in the stomach

- impact of stomach acidity on drug stability

- interaction of drugs with specific receptors

- initiation of pharmacological effects

- blinding of drugs to plasma proteins

- influences on drug availability

- absorption of drugs into the bloodstream

- interaction with intestinal enzymes

- enzymatic processes in the liver metabolize drugs

- drug metabolism affects bioavailability

- lipophilic drugs may accumulate in fatty issues

- fat-soluble drugs have specific distribution patterns

- cellular uptake of drugs

- intracellular drug activity and impact

- primary organ for drug metabolism

formation of metabolites for excretion