Hypothalamus

Supraoptic

Paraventricular

ADH/Oxytocin
Osmoreceptors are located in Anterior hypothalamus

Under control of Leptin which Increases TRH production

Production center for TRH

Corticotropin Release Hormone

Supraoptic

ADH/Oxytocin/CRH

Medial Preoptic

GnRH

suprachiasmatic

Circadian Clock

Tuberal

Ventromedial

Satiety

Lesion will cause result in hyperphagia
Stimulation will cause cessation fo feeding

Anterior

Stimulation will decrease Body Temperature/ Parasympathetic
Lesion will result in hyperthermia

Arcuate

Release of GHRH

Under dual antagonistic control of Leptin

Leptin will increases production of proopiomelanocortin (POMC) which is converted into α-MSH and that acts on the paraventricular nucleus to increase TRH.

It decreases the production of agouti-related protein (AgRP ), which acts on the paraventricular nucleus to decrease TRH

Dorsomedial

GI Tract

Under tonic inhibition

Periventricular

GIH or somatostatin release

Dopamine or PIF release

mammillary

mammillary

Suckling Reflex

Posterior

When stimulated increased shivering
Sympathetic Nervous System
Lesion (Horners) will increased BP and decrease Body Temp which may result in shivering

Appetite and Thirst regulation
Lesion of the lateral hypothalamus leads to loss of appetite (aphagia), starvation, and death