ANEMIA of CHRONIC INFLAMMATION

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VITAMIN DEFFICIENCY DISEASES

由uppalapati dhanush

DEPRESSION

由Amit Bal

Genetic Disorders

由Olivia Gillespie

Asthmatic 8yo male

由Mariah Boultinghouse

Treatments

Erythropoisis stimulating agents

Treat inflammation

Treat underlying cause of inflammation

Blood transfusions

DIAGNOSTIC LABS

Increased Ferritin levels

Low serum iron

Decreased Transferrin saturation

CBC - low RBCs

Brenda Mitchell

Liver

Bone Marrow

Pluripoint stem cells

Proerythroblasts

Multiple divisions

accumulates Hemoglobin

Nucleus lost

Loses mitochondria and ribosomes

Reticulocytes released into circulatory system

Mature Red Blood Cells

Spleen

Iron stored as Ferritin

ANEMIA of CHRONIC INFLAMMATION

Systemic Inflammation

Auto Immune diseases, Infections, Malignancies, Burns, Trauma

Increased Cytokine production

Decrease Iron availability

Increased RBC Destrucion

Decrease RBC productio