作者：Adilah Jamil 10 年以前
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Gram Negative Bacteria
Natural transformation
Constitutes a major gene transfer
mechanism in the prokaryotes
Researchers found the integration of foreign DNA into the genome of the Gram-negative Acinetobacter sp. BD413 during transformation.
The active uptake of cellular DNA
The Mechanism & Function of Natural Competence
Gram Negative bacteria take up DNA
in two stages :
DNA translocation (across the
inner membrane)
DNA uptake (across the outer membrane)
Gram Negative Bacteria
Research
NIAID-funded researchers are exploring these related to
Gram negative bacteria and the diseases they cause.
Researchers are unraveling the molecular
mechanisms of drug resistance
to identify novel strategies to
combat these pathogens
New drugs to combat Gram negative bacteria
infections are needed.
Prevention
Vaccines are not available for most healthcare-
associated caused by Gram negative bacteria.
To reduce it, hand washing and having healthcare
workers wear gloves
Many infections occur through
cross contamination between people.
Characteristics
Thin peptidoglycan
High Lypopolysaccharides
Appear pinkish or red
Treatment
For example, the unique nature
of their cell wall makes them resistant
to several antibiotics
Can be difficult because of several
unique features of this bacteria
Transmission
This can lead to pneumonia and such infections of the :
urinary tract
joints
bones
bloodstream
Bacteria enter the body through :
wounds
ventilators
urinary
