类别 全部 - treatment - transmission - bacteria - transformation

作者:Adilah Jamil 9 年以前

319

Gram Negative Bacteria

The integration of foreign DNA into the genome of Gram-negative bacteria, such as Acinetobacter sp. BD413, occurs through a process known as natural transformation, which is a significant gene transfer mechanism in prokaryotes.

Gram Negative Bacteria

Natural transformation

Constitutes a major gene transfer mechanism in the prokaryotes

Researchers found the integration of foreign DNA into the genome of the Gram-negative Acinetobacter sp. BD413 during transformation.

The active uptake of cellular DNA

The Mechanism & Function of Natural Competence

Gram Negative bacteria take up DNA in two stages :

DNA translocation (across the inner membrane)
DNA uptake (across the outer membrane)

Gram Negative Bacteria

Research

NIAID-funded researchers are exploring these related to Gram negative bacteria and the diseases they cause.
Researchers are unraveling the molecular mechanisms of drug resistance
to identify novel strategies to combat these pathogens
New drugs to combat Gram negative bacteria infections are needed.

Prevention

Vaccines are not available for most healthcare- associated caused by Gram negative bacteria.
To reduce it, hand washing and having healthcare workers wear gloves
Many infections occur through cross contamination between people.

Characteristics

Thin peptidoglycan
High Lypopolysaccharides
Appear pinkish or red

Treatment

For example, the unique nature of their cell wall makes them resistant to several antibiotics
Can be difficult because of several unique features of this bacteria

Transmission

This can lead to pneumonia and such infections of the :
urinary tract
joints
bones
bloodstream
Bacteria enter the body through :
wounds
ventilators
urinary