Organigram

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Impact of Heart Disease in Canada

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Impacts of Heart Diseases in Canada

由Gabriela Lee Confesor

Artificial Cardiac Pacemaker

由Emma Darrigan

Heart Failure

由R G

Heart failure with reduced ejection fraction

Renin angiotensin aldosterone system

angiotensin ll

Valsartan( inhibit angiotensin ll)

AT2 receptor

increase vasoconstriction

increase heart hypertrophy

increase aldosterone

increase blood pressure

Natriuretic peptide system

natriuretic peptides

Sacubitril( inhibit enzyme neprilysin) produce inactive fragment

increase bradykinin and angiotensin ll

increase vasodilation

decrease heart hypertrophy

decrease aldosterone

decrease blood pressure