Mendelian Genetics

A variation of information that is used in chromosomes

Organisms will have 1 or more

One gene compy which is randomly selected

Punnett square

Used to predict

Genotypes

Phenotypes

Familial hypercholesterolemia

Huntington's disease

Neurofibromatosis

Achondroplasie

Hypophatemic rickets

Ornithine transcarbamylase deficiency

Phenylketonuria (PKU)

cystic fibrosis

Sickle cell anemia

Tay-sachs diease

Hemophilia A

Duchenne Muscular dystrophy

Disadvantages

Creation of deadly genetic viruses

Can affect relationships with the knowledge of a genetic mutation

Uses

First were developed in late 1900s
CRISPR made is easier to edit genes

Original Human Genome Project took 13 years and cost 3 Billion$ now it costs 1000$ and takes three days

Makes changes in

Benefits

removes

Faster growing plants and animals

Pairs

Autosomal

Ever genertation

affect offspring has affected parent

Autosomal

Offsprings have parents that are carriers

.

Not typically seen in every generation

X linked

Females more frequently affected

Can have affected Males and Females in same generation

X linked

Subtopics more frequently affected

Subtopicected males often present in each generation

Mitochondrial

affected both genders

Subtopicappear in ever generation

Leber's heredity optic neuropathy, kearns sayre syndrome

Preferred method of collecting family history info

Shows the presence or absence of a

Inheritance patters in a

Three major patterns are

Life

Czech Republic July 20, 1822-January 6, 1884

Austrian monk, born as Johann but took on Gregor as a monk

Father of Genetics
Even though he didn't know about

Poor Farming Family

Education

2 year philosophy program at the philosophical institute of the university of Olmutz

Failed teacher exam send to University of Vienna for 2 years to benefit from a new proram of scientifc instruction

Devoted his time while at vienna to physics and mathematics

Also studied anatomy and physiology of plants

Experiments

Plant Hybridization

Conducted studies with edible pea plants (Pisum Sativum)

Choose 7 traits expressed in a distinctive manner such as plant height and seed colour

He crossed varieties that were different in one trait. Tall x Short

Showed different

Recessive

It is only observable when it is the only allele in the individual

Weaker

Is not observable

Dominant

It is the only observable trait when it is present

Stornger

is observable

Subtopic

Not Relevant

Unrelated to whether the trait is good or bad

Most beneficial and least beneficial

Most and least common trait in population

Deoxyribonucleic acid

Double helix

Adenine & Thymine

Guanine & Cytosine