jonka R G 16 vuotta sitten
363
Lisää tämän kaltaisia
RB
EB
Preventable Blindness
STD in U.S.
C. pneumoniae
C. psittaci
C. trachomatis
Urethritis
Reiter's syndrome
Reactive arthritis
Painful urination
Cervical infection
Asymptomatic
Infants
Pneumonia
Conjunctivitis
Fallopian Tube
P.I.E.
Ectopic Pregnancy
Infertility
PID
Increased HIV susceptibility
Gas usually located near a mucosal surface
From the short-chain fatty acids
Veillonella
Anaerobic streptococcus
Peptostreptococcus
Pigmented
Clostridium
C. botulinum
Botulism
Weakness of UE
Blurred vision
Nausea
Epi
Honey
Improperly canned veggies
Spores are ingested.
C. tetani
Tetanus
Trismus
Lockjaw
C. perfringens
Wound infections
Most common cause of wound infections among the clostridium species.
Gas gangrene
C. difficile
Soil
GI
CCF agar
CCFA = cycloserine-cefoxitin-fructose agar
Compare to Campylobacter jejuni.
Toxin test
Gold standard for diagnosis
Pseudomembranous colitis
Antibiotic-associated diarrhea
Subtopic
Legionella
Haemophilus
H. influenzae
Francisella
F. tularensis
Bordetella pertussis
Toxins
Dermonecrotic toxin
Tracheal cytotoxin
ciliostasis
Adenylate cyclase / hemolysin
Adhesins
Ptx
Pertussis toxin
Fha
Filamentous hemagglutinin
IgA protease
prevents opsonization
LOS
Motility
Petechiae on trunk/appendages
N. gonorrheae
Antiphagocytic capsule
RMP
protects other surface antigens from bacteriocidal Ab
Phase Variation
allows escape from humoral immune responses.
Opa
invasion
Pilin
initial attachment
Por
intracellular survival
inhibits phagolysosomal fusion
Women
Men
N. meningitidis
Attachment pili
Antiphagocytic polysacc capsule
W135
Y
C
B
No Vaccine!
A
P. aeruginosa
Halophilic
Is it halophilic?
Is it a facultative anaerobe?
Does it ferment carbs?
Urease
Does it have the enzyme urease?
Does it lead to type B gastritis?
Does it cause duodenal ulcers?
Campylobacter
Different from Vibrios because:
1) Microaerophilic
2) Resistant to many antibiotics
3) Very small
4) No carb metabolism
5) Not halophilic
Antibiotics
Metabolism
DNA % G+C ratio
Oxidase
Carbohydrates
Motile
Comma-shaped
Very small
Microaerophilic
C. fetus
Systemic bacteremia
Often fatal
Rare
Immunocompromised
C. jejuni
Thermophilic
Treatment
Erythromycin
Children
Ciprofloxacin
Adults
Self-limiting
Oral rehydration
Epidemiology
Endemic worldwide
Summer / Early fall
Poorly cooked food
Milk
Meats
Chicken
Clinical
Sequelae
Guillain-Barre syndrome
Acute demyelinating disease of the PNS
Symptoms
10+ bowel movements per day
Fecal leukocytes
Bloody stool
H. Pylori
Vibrio
V. alginolyticus
V. vulnificus
V. parahaemolyticus
V. cholereae
Enterobacteriaeceae
Organisms
Yersinia
Virulence Factors
Yops
YopM
prevents platelet aggregation by interacting with thrombin
YopE
YopH
Plague
Pneumonic
Bubonic
Bubo
Swollen lymph node
Endemic in Southwestern U.S.
Zoonotic
Rats
Fleas
Klebsiella
Salmonella
Shigella
E. Coli
Characteristics
Catalase
Spores