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Luokat: Kaikki - edema - diuretics - hypertension

jonka Courtney Rockwood 6 vuotta sitten

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Potassium-sparing Diuretics

Potassium-sparing diuretics, such as spironolactone, function by blocking aldosterone in the distal tubule, leading to sodium excretion and potassium retention. This mechanism results in a diuretic effect that helps to reduce blood pressure, alleviate edema, and decrease pulmonary congestion, which in turn lessens the workload on the heart.

Potassium-sparing Diuretics

Lisää tämän kaltaisia

Diuretics

Diuretics

luonut Felicia MedStudent

Peaches

Peaches

luonut Andrew Carter

HYPERTENSION

HYPERTENSION

luonut yashwit polapragada

Chapter 28 Diuretic Drugs

Chapter 28 Diuretic Drugs

luonut Songyuan Ma

Potassium-sparing Diuretics

Prototype Drug

Aldactone (trade)

spironolactone (generic)

Med examples

triamterene (Dyrenium)

spironolactone (Aldactone)

amiloride (Midamor)

Nursing Considerations

* do not use in pts' with hyperkalemia or anuria * monitor K+ levels frequently * obtain W daily, monitor UO * avoid foods high in potassium, such as avocados, peaches, bananas, nuts, and broccoli

Off label uses

ascites

acne

treating female pattern hair loss

Side Effects/Adverse Effects

hyperkalemia, lethargy, confusion, irregular menses, hirsutism

Mechanism of Action

Conditions Treated: * hypertension * hyperaldosteronism * adjunct to treatment with antiarrhythmics/digoxin

Therapeutic Effects: * reduces BP * reduces edema/pulmonary congestion * decreased workload on heart

Aldosterone action is blocked in distal tubule, causing Na+ excretion in the urine; blocks K+ secretion through tubule, resulting in retention of K+. Achieves diuretic effect by loss of Na+ to offset retention of K+ balance.