Kategóriák: Minden - stimulant - administration - addiction - concerns

a Angela Matthews 4 éve

210

Alcohol

Methamphetamine is a powerful stimulant that affects the central nervous system. It can be used in various ways, including swallowing, snorting, injecting, and smoking, each producing different intensities and durations of euphoria.

Alcohol

Psychedelics

Medically

Used as an anesthetic and in narcolepsy treatment

Used for neurochemistry and brain mapping

Historically
DMT used for thousands of years by Amazonian Tribe

Activated by brewing rainforest plants in a tea

Religious
Native American Church

Uses peyote in religious ceremonies (nondrug use)

Stimulants
Hallucinogens
Effects are similar to ecstasy, is habit forming in rats and may cause withdrawal symptoms
In high doses, causes dissociative hallucinogenic effects, like PCP and ketamine, less likely to cause addiction or dependence
Can cause sedation and memory loss, recreational effects are similar to PCP, also has low to moderate addiction potential
May cause mania, delirium and disorientation, is moderately addictive and there is a possibility of developing psychological issues
Dissociative, distorts sight and sound, hallucinogenic effects can cause trance-like states, anxiety and dysphoria
Similar to ecstasy, causes increase in empathy and affection, as well as visual hallucinations, may also cause extreme anxiety and feeling of doom
Causes dehydration and raises body temperature, can lead to fatal medical complications due to hyperthermia and dehydration, especially when combined with alcohol
Increased empathy and emotional connection, elevates mood and facilitates mental and physical euphoria, can create mild hallucinations like color change and heightened audio
Mescaline/peyote
Color enhancements, euphoria, increase in introspection, can cause nausea and vomiting due to peyote's bitterness

Low risk of psychological addiction, not chemically addictive

Increases empathy, euphoria and alters thinking. Some species may cause open and closed eye visuals
Alters awareness/perception, may cause hallucination, not chemically addictive, but may still cause paranoia and anxiety
Effects of mescaline are similar to LSD

Dried leaves

Chewing leaves and holding them in your mouth

Snorting, sublingual and absorbed through the mucosa in the mouth

Fresh or dried buttons, capsules, dried powder or a teas

DMT

Eat them straight, brew a tea, mix them with other foods

Tablet, capsule, powder and liquid

Snorting

Pure liquid form

may be very potent

Liquid on sugar cubes

Tablets, called Microdots, or capsules

Thin squares of gelatin

Called "window panes"

Blotter Paper

LSD soaked into sheets of absorbent paper with colorful designs, cut into small individuals dosage units

Most common form

Other/Street Names

LSD
Acid, blotter, doses, dots, trips, mellow yellow, window pane, purple dragon
DXm
Dextromethorpan
Phencyclidine
Salvinorin A
251-NBOMe. 251
MDMA, molly
Psychedelics stimulate or suppress the activity of neurotransmitters that they are chemically similar to
Overdose via mistaken identity in general
N-Bomb is fatal in high doses, effective dose is less than a milligram while similar synthetic hallucingoens require about 3 grams
Several overdoses caused by mistaken identity
Psilocybin mushrooms are difficult to distinguish from deadly mushrooms
Death Caps can look identical and grow in the same places
Restricted to veterinary use
Not used in humans
Salvia is federally legal, some states consider it a controlled substance
Peyote
Schedule I drug (illegal); with religious exemptions

Listing peyote as a Schedule I drug does not apply to the nondrug use of peyote in religious ceremonies of the Native American Church

Individuals manufacturing or supplying peyote to the Native American Church is required to obtain annual registration and to comply with all other law requirements

Members of the Native American Church do not have to register their peyote use when used for a religious ceremonies

GHB
Psychoactive drug that naturally occurs in the brain
DXM
Common ingredient in cough suppresant
Ketamine
Precursor to PCP, synthesized for the same purpose
PCP
Synthetic drug that also causes dissociative hallucinations

Originally synthesized as an anesthetic, discontinued use in humans in the 1950's

Salvia
Psychoactive drug that comes from "Salvia divinorum" a plant native to the mountains of Oaxaca, Mexico

Unique in chemical structure compared to other natural psychedelics

Not alkaloid, is terpenoid, a broad class of organic chemicals

N-Bomb
Synthetic designer drug used for neurochemistry and brain mapping
Mescaline
Naturally occurring in some species of cactus (i.e. peyote)
Ecstasy
Hallucinogenic properties are less pronounced, mood-altering and stimulant effects are more noticeable than in other psychedelics
Psilocybin
Termed "magic mushrooms"

Wide variety of hallucinogenic mushrooms

Legal state is ambiguous as the are naturally found in many parts of the world

Ololiuqui
Naturally occurring in morning glory seeds

Not commonly used due to unpleasant side effects

Dimethyltryptamine (DMT)
Has shorter effects than other psychedelics, lasts ~1 hour
Naturally occurring, found in nuts and bark of certain trees in South and Central America

Phalaris, Delosperma, Acacia, Desmodium, Mimosa, Virola and Psychotria genera

Also found in leaves of citrus plants and leaves, seeds and inner bark of "mimosa tenuiflora," which has become a source of livestock poisoning

Acid, Lysergic Acid or LSD
Developed from ergot, a mold found on rye grain

Opioids

Binds to opioid receptors in brain, spinal cord and peripheral tissues, reducing the amount of pain messages being sent to the brain, curbing the feeling of pain, triggers the dopamine reward system
Dopamine "high"
Opioid craving
Pain relief
Medicinal
Some can be used to treat coughing and diarrhea
Used to treat moderate to severe pain
Drowsiness, constipation nausea, slowed breathing, unconsciousness, coma
Withdrawal symptoms

Restlessness, muscle and bone pain, insomnia, diarrhea, vomiting, cold flashes with goose bumos

Physical dependence, tolerance, addiction
"Street" Routes

Least Common

Injection
Intranasal

Most Common

Medical Routes
Cutaneous

Topical application to the conjunctiva of the eyes, nasopharynx, oropharynx, vagina, colon, urethra, and bladder

Pulmonary

Uses the large surface area of the pulmonary epithelium and mucous membranes

Intraperitoneal

Injected into the large surface lining the abdominal cavity

Intrarterial

Injected directly into an artery

Local Effects

Intraspinal

Injected into spaces in and around spinal cord

Morphine and fentanyl

Intravenous

Immediately circulates systemically

Intramuscular

Injected into muscle, commonly deltoid or vastus lateralis

Not recommended for pain management, often hurts and opioids are absorbed variably and unpredictably

Subcutaneous

Absorption may take longer than intravenous injection, but provides rapid pain relief without having to access a vein

Rectal

Used when patients can't swallow or intravenous sites are unavailable

Sublingual

Goes under the tongue

Absorbed rapidly

Aerosol

Uses IV preparations in a nebulizer

Causes rapid peak blood levels

Transmucosal

Absorbed via oral mucosa

Fentanyl lozenge

Very expensive

Transdermal

Drug applied to skin to absorb slowly, may use an adhesive patch

Only opioid available for this route is fentanyl

Takes 12-22 hours to work

Enteral Tubes (Feeding Tubes)

Nasogastric (NG), percutaneous endoscopically placed gastrostomy (PEG) tubes, jejunal (J) tubes

Allows for bitter opioids like concentrated liquid morphine to be administered easily

Overcomes patients inability to swallow

Used for drug delivery if already present

Oral

Preferred route and medications are usually cheaper

Partial Agonists
Meptazinol, buprenorphine
Agonists/Antagonists
Nalorphene, pentazocine, nalbuphine, butorphanol, dezocine
Antagonists
Inhibits physiological response

Naloxone, naltrexone, nalmefene, diprenorphine

Agonists
Initiates physiological response

Morphine, codeine, oxycodone, pethidine, diamorphine, hydromorphone, levorphanol, methadone, fentanyl, sufentanyl, remifentanyl, tramadol, tapedolol

Fully Synthetic Opiates
Completely manmade

Fentanyl (many times stronger than other opioid pain relievers), pethidine, levorphanol, methadone, tramadol, dextropropoxyphene

Semi-synthetic Opiates
Made from natural opiates

Hydromorphone, hydrocodone, oxycodone, heroin (illegal)

Natural Opiates
Alkaloids, nitrogen-containing base compounds found in plants (i.e. opium poppy)

Morphine, codeine, thebaine

Societal costs
Loss of relationships due to addiction, loss of support from family and friends, loss of job/income
Serious issue in rural communities
Few treatment programs, low education on drug use, abuse and addiction, opioids are easy to get in rural communities

All of this affects the economy, which can increase the number of individuals using opioids

Economic burden in the U.S. is ~$78.5 billion a year
Healthcare cost, loss of productivity, addiction treatment, law enforcement involvement
Misuse and addiction of opioids is a crisis
128 people a day in 2018 died from opioid overdose
HIV risk from reusing unsterile needles
State
Some states require physicians to report opioid-dependent
Imprecise legal definitions of terms allows patients to be confused for addicts
Permit prescribing opioids for pain, do not recognize the medical value of controlled substances
Federal
Providing opioids to addicts is illegal unless the physician is separately registered to treat addiction

Addendum to Harrison Law, 1919, made it illegal for physicians to prescribe opiates to treat opiate addiction

Federal controlled substances law affirms medical value of many drugs that are controlled substances, states that opioids may be used for extended treatment of patients with intractable pain
Illegal
Heroin, illegal prescription drugs coming across the border
Legal
Prescription pain killers (OxyContin, morphine, codeine, etc.)

Inhalants (Gasoline)

Street Names for Using Inhalants
Bagging, Huffing, Glading
Air blast, bold, chroming, discorama, glad, hippie crack, moon gas, oz, poor man's pot, rush, snappers, whippets, whiteout, bullet bolt, highball, laughing gas
Fumes inhaled by nose or mouth (i.e. gas siphoning)
Liver/Kidney/Brain damage, hearing loss, bone marrow damage, loss of motor control and limb spasms due to nerve damage, delayed behavioral development
Slurred/distorted speech, lack of coordination, euphoria, dizziness, hallucination, delusions, vomiting, drowsiness, headache
Immediately enters the blood stream through the lungs
Slows brain function

Works similarly to alcohol, doesn't last as long

Liquid that vaporizes at room temperature

Nausea, loss of appetite, sweating, problems sleeping, mood changes

Health problems, inability to meet responsibilities at work, school or home

Coma, death, suffocation from use in closed spaces

Toxic reaction that leads to serious symptoms, seizures or death

Predominantly recreational use among children and adolescents
Some states restrict sale and distribution of substances to minors that can be used as inhalants
Not federally regulated

Meth

Smoked
Gives an intense "rush"
Swallowed
Euphoria, but no intense "high"

Produces effects after 10-20 minutes

Injected
Gives and intense "rush"

Doesn't last long

Snorted
Euphoria but no intense "high"

Produces effects after 3-5 minutes

Addiction, paranoia, hallucination, repetitive motor activity, changes in brain structure and function, deficits in thinking and motor skills, increased distractibility, memory loss, aggressive/violent behavior, mood disturbances, severe dental problems, weight loss
Hyperthermia, rapid, irregular heartbeat, increased attention, decreased fatigue, increased activity and wakefulness, euphoria and rush, increases respiration
Laws enforced by Drug Enforcement Administration (DEA)
Comprehensive Methamphetamine Control Act (1996)
Regulates mail order and chemical companies selling precursor chemicals
Federal Controlled Substance Analogue Enforcement Act (1986)
Attempted to curb growing use of designer drugs
Methamphetamine Precursor Control Policies
First began in 1983, banning possession of precursors and equipment for meth production
Controlled Substances Act (1970)
Mounted educational program against meth
Regulates importation, manufacture, possession, use and distribution of meth
Foreign Drug Cartels
Methods

Alternative Air Transportation

Drones

Very little legislation regulating drone use

Chemical Masking

Cartels use chemical processes to change appearance

Can be smuggled in clothes, oils, plastics, metals, pet food, etc.

Camouflaging it in Legal Shipments

Authorities have limited ability to inspect shipments, especially ports due to mass movement of international trade

Maritime, air and land transportation

Cyclists

Buses

Ambulances

Low probability authorities will detain emergency vehicles

Manufacture and smuggle meth over the border
Illegal for recreational use
Combat Methamphetamine Epidemic Act of 2005
Regulates over-the-counter sales of ephedrine, pseudoephedrine and phenylpropanolamine (no longer OTC) because they're used in the manufacture of illegal drugs
Schedule II of the Controlled Substances Act
Approved for pharmacological use in treating ADHD and treatment-resistant obesity

Named Desoxyn, manufactured by Ovation Pharmaceuticals

Casual use to some extent
Often leads to addiction
Traditionally
Man-made version of ephedra shrub

Ephedra has been used in Chinese medicine for over 5,000 years

Used to treat asthma, bronchitis, hay fever, cold symptoms

Socially
Increased ability and motivation to speak with others
Enhances confidence
Reduces inhibitions
Medicinally (Methamphetamine Hydrochloride)
Treats attention disorders i.e. ADHD

Other "Street Names"

When Using Meth
"Getting geared up," "Chicken flippin,'" "Hot rolling," "Fried," "Foiled," "Speed freak," "Tweaking," "Scattered," "Spun out," "Zooming."
Meth Combined with Other Drugs
Biker Coffee, Twisters, Hugs & Kisses, Fire, Shabu,Party & Play
Scooby Snax, Wash, Garbage
Shards, Speed, Stove Top, Super Ice, Tina, Trash, Tweak, Uppers, Ventana, Vidrio, Yaba, Yellow Bam, Jenny Crank diet
Hanyak, Hiropon, Hot Ice, Ice, Kaksonjae, LA Glass, LA Ice, Meth, Methlies, Quick, Poor Man's Cocaine, Quartz
Chalk, Chicken Feed, Crank, Cristy, Crystal, Crystal Glass, Crystal Meth, Go Fast, Gak, Christina, Cookies
Batu, Black Beauties, Blade, Cotton Candy, Dunk, Go-go juice, No Doze, White Cross, Pookie, Rocket Fuel
Hazardous Waste from Meth Manufacturing

Labs produce 5-7 lbs of toxic waste per pound of meth produced

Often disposed of improperly

Contaminates soil and water supplies

Chemical-stained cloth and coffee filters, glassware, baking dishes, hoses, lithium batteries, propane tanks, pseudoephedrine blister packs.

Chemical Containers

Acid, drain cleaner, iodine, rubbing alcohol, starter fluid, toluene, etc.

Medical concerns

Heart attack, brain damage coma, death

Increased high-risk behavior and possible suicidal behavior
Grades and work output drops, unemployment, financial strain, homelessness
Interpersonal relationships

Violent mood swings, individual may shirk responsibilities and obligations in favor of using meth

Anxiety, depression, fatigue, increased appetite, psychosis

Co-occurring disorders (i.e. addiction and anxiety)

Inability to self-regulate how much meth is used and how often

Compulsive drug-seeking

Meth used in a binge pattern

Used every couple hours for several days to prolong high

Preschool/School-age children

Significant attention impairment, cognitive and behavioral issues in terms of self-control and executive function.

Toddler

Delayed motor development

Infancy

Decreased arousal, increased stress, poor quality of movement

Mixing meth and other drugs

May lead to overdose

May lead to death

Overdose
Dependence

May lead to addiction

How It Work

Forces neurons to release stored noradrenaline and dopamine at once

Increases dopamine in brain by ~10x the amount of any pleasurable activity

Effects CNS
Colors
Impure meth

Blue, yellow, orange, pink, brown, etc.

Color depends on how it's made and what it's cut with

Pure meth

Translucent or white

Meth Base (less common)
Waxy, gooey oil
Pills
Crystalline (common)
Powder (common)

Caffeine

Coffee may become a luxury
Only Hawaii and California can produce coffee beans

Hawaii

Land is expensive, so coffee prices increase

California

Doesn't get enough water

Climate change is decreasing coffee bean yield
Increasing temp has allowed fungus (hemileia vastatrix) to invade

Causes gradual yellowing and decaying of leaves, leaving berries at the mercy of animals and weather conditions

Coffee tree must have specific balance of sunlight, soil pH, water and temperature to thrive
Tropical Economical Collapse
Many tropical areas rely solely on coffee bean exportation
Over consumption
Tremors, nausea, vomiting, very fast/irregular heart beat, confusion, panic attacks, seizures
Over 90% of adults use caffeine regularly
May lead to heart attacks
Withdrawal
Headache, fatigue, low energy, depression, anxiety, tremors, poor concentration
Snack bars/energy drinks
Energy shot, 1oz

215 mg

Energy drink, 8oz

29 mg

Guarana
Chocolate
Dark

59mg/100ml

Milk

20mg/100ml

Coffee
Instant, decaf
Instant, 8oz

62 mg

Espresso decaf, 1oz
Espresso, 1oz

64 mg

Brewed, decaf, 8oz
Brewed, 8 oz

96 mg

Sodas
Root beer, 8oz
Citrus, 8oz

0 mg

Colas may not contain more that 6mg/ounce
Teas
Ready-to-drink, 8oz

19 mg

Brewed green, 8oz

28 mg

Brewed black, decaf, 8oz

2 mg

Brewed black, 8oz

47 mg

Long term effects
Nervousness, difficulty sleeping, anxiety, muscle tremors and weakness, fatigue, poor appetite, nausea, low blood pressure, etc.
Headache, lack of concentration, stomach pain
Fast breathing and heart rate
Dehydration and increased need to urinate
Irritability and anxiety
Restlessness, excitability and dizziness
Increased alertness, activity, body temperature
Blocks body's ability to feel tired
Blocks adenosine receptors in the brain
Allows dopamine to be active
Most coffee imports are tax free

Excludes coffee containing syrups or sauces

Guidelines for FDA inspection of samples

Over 1000; 20 bag samples

201-1000 bags; 15 bag samples

101-200 bags; 10 bag samples

100 bags or less; 6 bag samples

No limit on importation amount for coffee or tea
Make transportation plans for product once it enters US
List documents you need for customs and have them handy

Hire customs broker to manage importation

Open credit line to avoid hang-ups, refrain from paying in cash

Credit line should outline ports of entry in US

Designate the territory of growing and make sure it's exclusive for your use
Negotiate contract with grower looking to export to America

Outline payment method

Must be named representative of contract

Process

Must fill out Customs and Border Protection form five days before import arrives

Importer Security Filings filed no later than 48 hours before shipments estimated time of departure from last foreign port

Fill out Country of Origin certificate

Mark Country of Origin clearly on each bag

Not strictly regulated; FDA suggests no more that 400 mg/day for a healthy adult, discouraged for children
Can be administered intravenously, but not common
Usually oral

What it's used for

Medication
Effective treatment for migraines
Found in many over-the-counter pain relievers
Psychoactive drug

Tobacco

Oral - dissolves
Oral - stays between lip and front teeth
Inhalation of Smoke/Vapor
Increase cholesterol deposition
Decreases blood oxygen levels
Heart disease
Heart Attack
Increases blood flow to heart
Atherosclerosis
Increase heart rate/blood pressure
Tobacco Control Act (2009)
Bans cigarettes with characterizing flavors except menthol and tobacco
Tobacco companies and suppliers must register with FDA annually

Must open facilities for FDA inspection every 2 years

Preserves state, local and tribal authority

May regulate tobacco in certain respects

Requires disclosure of tobacco ingredients on packaging
"Modified Risk" claims must be supported by scientific evidence

Tobacco companies must file an application for a modified risk tobacco product and be given the order to advertise as such

Requires smokeless tobacco products to have warning labels

Ads

Warning label must cover at least 20% of ad area

Packaging

Must be on two principle sides and cover at least 30% of packaging

May cause mouth cancer, is addictive, is not a safe alternative to smoking, may cause gum disease and tooth loss

Allows FDA regulation of tobacco

Can regulate nicotine and ingredient levels

Restricts tobacco marketing and sales to youth

Bans sale to minors, vending machine sales, sales with packages of less than 20 cigarettes, tobacco brand sponsorship of sports, entertainment events, social and cultural events, free giveaways of sample cigarettes.

Manufacturing in US

Manufacture of Processed Tobacco

For businesses that manufacture processed tobacco

For businesses that manufacture tobacco products

Consumer Use
Must be 21
Export
Guidelines

Not sold or offered for sale in domestic commerce

Labelled on outside of package that it's intended for shipping

Not in conflict with laws of country it's exported to

Must be in accordance with the specifications of the foreign purchaser

Do not have to report to FDA

Tobacco Export Warehouse Proprietor

For businesses looking to export American tobacco

Import
Have to report to FDA
Permits

Tobacco Products Manufacturer

Importers may need this depending on how they prepare their product for sale

Importer of Processed Tobacco

For businesses wanting to import processed tobacco to US

Don't need if you already have Tobacco Importer Permit

For anyone who wants to import foreign tobacco to US

Cuban Cigars

Cannot be imported commercially

Can be imported personally as long as you have them with you at the border.

Tobacco Importer Permit

Usually for businesses

May bring up to 1,000 cigarettes every 31 days from American Samoa, Guam, the Commonwealth of the Northern Mariana Islands or the US Virgin Islands

No more than 200 of the 1,000 can be sourced outside of these areas.

May not exceed US customs limit for personal use

May bring back 200 cigarettes AND 100 cigars at once w/o permit

Over 21
Recreation
Economic costs
Smoking-related illness costs ~$300 billion/year

~$5.6 billion in lost productivity from secondhand smoke

~$156 billion in lost productivity

~$170 billon in direct medical care

Lung Cancer
80% of people with lung cancer are smokers
Secondhand Smoke
Respiratory infections
Premature heart disease
Lung cancer
Causes change in brain
Mimics acetylcholine
Stimulates and then depresses cholinerergic receptors
Both stimulant and depressant
Dissolvable Products
Orbs, Sticks/Strips
E-cigarettes
Pen style, box style, rechargeable, variable voltage

Prefilled capsules, refillable capsules, disposables

Smokeless tobacco
Loose-leaf tobacco
Chewing tobacco
Water pipes (hookas)
Cigars
Cigarillos
Little Cigars
Cigarettes

Marijuana

Synthetic marijuana is illegal in Oregon
Legal for Recreational Use in Some States

Cannot take marijuana across state lines

Growing

May have 10 marijuana seeds

Individuals may grow up to 4 plants on their property

Distributions

Cannot use in bar/reseraunt

5 grams of cannabinoid extracts

72 ounces of a cannabinoid product in liquid form

16 ounces of solid cannabinoid product in solid form

May have 1 ounce on their person in public

May have up to 8 ounces of usable marijuana in their homes

Must have valid government issued photo ID

Must be 21 or older

Illegal at Federal Level
THC mimics brain chemical Anandamide
THC can bind to cannabinoid receptors altering psychological function

Activates reward system

Releases dopamine

Causes high, making people want more

Alters cerebellum/ganglia

Control posture, balance, coordination and reaction time

Alters hippocampus and orbitofrontal cortex

Involved in making new memories and change attentional focus

How It's Used

Industrial Hemp
Cannabis sativa with less than 0.3% THC

Production, possession and commerce legal in Oregon since 2010

Clothing, cosmetics, industrial materials, etc

Commercial
Production
Processing
Retail
Wholesale
Medical Use
Must have severe medical condition and diagnosed by doctor or osteopath

May have 18 immature plants, starts or seedlings

May have 6 mature plants

Personal Use
Decrease coordination/reaction time
Lower inhibitions
Distortion of time
Noises may seem louder
Colors may seem brighter
May worsen symptoms of mental disorders already present
May increase risk for depression
The "high" caused by dopamine release
Hallucinogenic
Causes changes in thought, emotion or conciousness
Stimulant
Increases CNS activity
See "Alcohol"
Poisoning
Can occur with edibles

People can eat much because edibles don't have an immediate effect

Use during pregnancy
impairs attention, memory and problem solving skills of children

May lead to problems with behavior

Affects brain development and establishing neural connections

Attention, memory and mood

Addiction
Affects job, relationship or school
Failure to quit using marijuana
Giving up social events to use marijuana

Routes of Administrations

Topical
Lotions, creams, oils, etc.
Edibles/oils
Smoking
Dried parts of cannabis plant
Concentrates
Lotions, patches oils, etc.

Also contain THC, CBD or both.

Edibles
Candies, brownies, cereals, drinks, etc.

CBD

The chemical used for pain relief

THC

The chemical that gets you high

Dried flowers, stems and leaves

Alcohol

Concerns

Social Consequences
Relationship Destruction
Job Loss
Bankruptcy
Intervention
Irreversible Effects to the Body
Heart attack, liver failure, etc.
Binge Drinking
Social/Physical Consequences

Common Forms

Isopropanol

Used for disinfecting and cleaning (rubbing alcohol)

Methanol
Poisonous when consumed

Used in fuel, antifreeze, paint thinner, etc.

Ethanol
Consumable

Spirits

Gin, whisky, vodka, tequila, absinthe, etc.

Wine

Beer

Effects

Long Term
Irregular Heart Beat
High Blood Pressure
Stroke
Cardiomyopathy
Fatty Liver
Cancer
Reduced white and grey matter in the brain
Shortened Attention Soan
Memory Loss
Short Term
Difficulty concentrating
Raised Blood Pressure
Passing out
Reduced Body Temp.
Mood Swings
Vomiting
Loss of coordination
Poor judgement/lower inhibitions

Classification

Depressant
Relieves Anxiety
Modified Equilibrium
Slurred Speech
Relaxation

Regulation

Importation
Customs paperwork
Obtain Certificate of Age and Origin for certain wines and spirits
Must pay taxes, fees and duties
Must posses Certificate of Label Approval for each imported product
Must contract with an existing U.S. licensed importer
Must maintain and staff a business office in U.S.
Must have Federal Basic Importers Permit
Distribution
Distribution laws/regulations vary state to state

Oregon Liquor Control Commission

Also handles marijuana laws

Too many things to list; https://www.oregon.gov/olcc/Pages/index.aspx

Wine, Liquor and Malt Beverage Privilege Tax

Sale
Some states prohibit sale to pregnant women
Restrictions on alcoholic specials (two-for-one) and happy hours
Business cannot offer free alcohol with meals
Individual must present government issued photo ID

Driver's license, temporary permit, military license, passport, etc.

Business must have a liquor license
Individual must be 21 or older to buy alcohol
Possession/Use
Must have government issued photo ID
Legal age of 21

How it's Used

Dissolves things
Cosmetics/Perfumes
Combustion
Fuel
Disinfect
Rubbing Alcohol/Medical Disinfectant
Clean
Household Cleaners
Drink it
Recreational

Routes of Administration

Siphoning Fuel
Oral Consumption

How it Works

Endocrine System
Decreased Testosterone Levels

Acne

Easy Bruising

Erectile Dysfunction

Reduced Uptake of Calcium

Osteoperosis

Impair Gland Function

Hypoglycemia

Circulatory System
Poor Heart Function

Plugged Blood Vessels

Damaged cells

CNS
Factors Effecting CNS Impairment

Food Intake

The amount of alcohol/ time period over which it was drunk

Whether it's mixed with other drugs

How often the individual drinks

Genetic Background

Mood/psychological makeup of individual

Age, weight and sex

Women are usually smaller and lighter than men

Further concentrates the alcohol in their blood

Women produce less alcohol dehydrogenase than men

Brain

Damage/Kill Neurons

Dulled hearing

Impaired vision

Weakened muscles

Foggy thinking/memory

Slowed reaction time

Digestive System
Stomach

Alcohol increases acid content in the stomach

Sever stomach pain/sores

Liver

Free radicals damage the liver

Liver cirrhosis

~ 80% of alcohol absorbed in the small intestine
~ 20% of alcohol absorbed in the stomach